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Keywords: insulin
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Journal Articles
J Exp Biol (2024) 227 (10): jeb247537.
Published: 21 May 2024
... [glucose]. We also challenged animals with glucose, insulin or insulin-like growth factor-1 (IGF-1) injections and measured the rate of glucose clearance in normoxia and hypoxia. We found that: (1) blood [glucose] increases in moderate hypoxia in queens and pups, but only in severe hypoxia in adult...
Journal Articles
J Exp Biol (2020) 223 (22): jeb226027.
Published: 23 November 2020
... and fitness is less clear. Here, we show that Drosophila exposed to hypoxia during their larval period subsequently show reduced starvation stress resistance and shorter lifespan as adults, with these effects being stronger in males. We find that these effects are associated with reduced whole-body insulin...
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Journal Articles
J Exp Biol (2018) 221 (13): jeb163840.
Published: 6 July 2018
... , Y. , Vieira , E. , Krook , A. , Björnholm , M. , Long , Y. C. , Kotova , O. , Zhong , Z. , Sakane , F. , Steiler , T. , et al. ( 2008 ). Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance . Cell   132 , 375...
Journal Articles
J Exp Biol (2018) 221 (Suppl_1): jeb161554.
Published: 7 March 2018
... the additional metabolic consequence of stimulating protein catabolism ( Brillon et al., 1995 ), the increasing levels of cortisol and decreasing secretion of insulin together drive plasma NEFA and milk lipid content in lactating NES ( Fowler et al., 2016 ) ( Fig. 3 ). Insulin is an important regulator of lipid...
Journal Articles
J Exp Biol (2016) 219 (19): 3003–3008.
Published: 1 October 2016
...Carolina Mengoni Goñalons; Marie Guiraud; María Gabriela de Brito Sanchez; Walter M. Farina ABSTRACT Worker honeybees ( Apis mellifera ) carry out multiple tasks throughout their adult lifespan. It has been suggested that the insulin/insulin-like signalling pathway participates in regulating...
Includes: Supplementary data
Journal Articles
J Exp Biol (2016) 219 (18): 2944–2954.
Published: 15 September 2016
... rate and physiological markers of hormonal stress response, energy availability and anaerobic respiration in blood plasma across five ecologically relevant temperatures (24, 28, 32, 35 and 38°C; 3 h exposure). Corticosterone, insulin and glucose concentrations all increased with temperature...
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Journal Articles
J Exp Biol (2013) 216 (10): 1771–1773.
Published: 15 May 2013
...Jun Murakami; Ryuichi Okada; Yutaka Fujito; Manabu Sakakibara; Ken Lukowiak; Etsuro Ito SUMMARY Insulin's action in the brain can directly alter cognitive functioning. We have recently shown that molluscan insulin-related peptides are upregulated following a conditioned taste aversion (CTA...
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J Exp Biol (2012) 215 (15): 2696–2702.
Published: 1 August 2012
...Xiao Li Zhao; Ana Regina Campos SUMMARY Whereas the pivotal role of insulin signalling in cell division, growth and differentiation is well documented, its role in the regulation of neuronal function and behaviour has recently become the focus of intense investigation. The simple organization...
Journal Articles
J Exp Biol (2012) 215 (8): 1373–1383.
Published: 15 April 2012
... to different scenarios. In response to fasting, adiponectin expression was up-regulated in adipose tissue, while the expression of its receptors increased in white and red muscle. Insulin injection decreased adipoR1 expression in white and red muscles. We deduce that the adipoRs in trout muscle show opposite...
Journal Articles
J Exp Biol (2011) 214 (9): 1599–1606.
Published: 1 May 2011
... changes in serum insulin level with the circulating leptin level and with the changes in body fat mass in S. heathi . An in vitro study showed insulin induced a significant increase in expression of leptin protein in WAT. The insulin-stimulated increase in leptin expression was associated with increased...
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Journal Articles
J Exp Biol (2009) 212 (10): 1553–1558.
Published: 15 May 2009
...Chunchun Han; Jiwen Wang; Liang Li; Zhongxian Zhang; Li Wang; Zhixiong Pan SUMMARY In order to obtain some information on how fatty liver arises in geese, we investigated the role of insulin and glucose in triglyceride (TG) accumulation in goose primary hepatocytes. Goose primary hepatocytes were...
Journal Articles
J Exp Biol (2008) 211 (18): 2943–2949.
Published: 15 September 2008
... at the end of the sampling period in all groups. Glucose clearance rates were not significantly different among test groups. A significant insulin response was observed in early lactation, no significant response was observed late in lactation and an intermediate response was observed late in the molt fast...
Journal Articles
Journal Articles
J Exp Biol (2008) 211 (5): 741–748.
Published: 1 March 2008
...Mi-Ae Kang; Tiffany M. Mott; Erin C. Tapley; Edwin E. Lewis; Shirley Luckhart SUMMARY Observations from nematodes to mammals indicate that insulin/insulin-like growth factor signaling (IIS) regulates lifespan. As in other organisms, IIS is conserved in mosquitoes and signaling occurs in multiple...