... in vivo) was greatest at the anterior ileum, and lowest at the colon. Ileal K + efflux was inhibited by both Scg-AST-6 and Locmi-FGLa/AST-2, with maximal inhibition at 10 −10 and 10 −11 mol l −1 , respectively. Both FGLa/ASTs also inhibited cAMP-stimulated K + efflux from the ileum. Locmi-FGLa/AST-2 also...

... and the cystic fibrosis transmembrane conductance regulator (CFTR) in the apical membrane. However, in the possum ileum, NKCC1 expression is low and secretagogues stimulate electrogenic HCO 3 – secretion driven by a basolateral NaHCO 3 cotransporter (pNBCe1). Here we investigated whether electrogenic anion...

... the basis of the secretory response of the possum ileum. In the Ussing chamber the secretory I sc is independent of Cl – but dependent upon Na + and serosal HCO 3 – /CO 2 , suggesting that secretagogues stimulate electrogenic HCO 3 – secretion. In agreement with this, serosal DIDS(4,4′-diisothiocyano...

... the response of the ileum and rectum to hindgut stimulants. Taken together, these data suggest that, in the initial phase of post-prandial diuresis, urine flow will exceed fluid uptake in the hindgut, thereby allowing excess water to be eliminated. Doses of Locusta -DH and Lom-K (100 nmol l −1...

... there was little apparent change in the level of MasFLRFamide III upon metamorphosis. Determinations of peptide levels in fractionated hemolymph of newly emerged moths revealed that levels of MasFLRFamide I and III could exceed 10 nmol l -1 . The actions of the three peptides were tested on the moth ileum...

... no effect on the ileum when salt bridges are used. Electrical parameters (I sc , V t , R t ) reflecting hindgut Cl − transport (J C1) before and after stimulation with cyclic AMP are the same whether or not salt bridges are used. We found no evidence of any coupling between J cI and J H / J OH...