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Keywords: glutamine synthetase
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Journal Articles
J Exp Biol (2016) 219 (20): 3218–3226.
Published: 15 October 2016
... was insensitive to amiloride (0.1 mmol l −1 ) or to a 10-fold elevation in seawater K + concentration (to 100 mmol l −1 ), suggesting that the mechanism does not directly involve Na + or K + transporters, but was inhibited by blockade of glutamine synthetase, the enzyme that traps ammonia-N to fuel the ornithine...
Includes: Supplementary data
Journal Articles
J Exp Biol (2013) 216 (21): 4025–4037.
Published: 1 November 2013
... exposed to HEA in a time-series analysis [500 μmol l −1 (NH 4 ) 2 SO 4 ; 15, 30, 45 and 60 min], as well as in a methionine sulfoxamine (MSOX) pre-injection experiment [to inhibit glutamine synthetase (GSase)]. These correlations consistently suggest that brain [T Amm ] is involved in the hyperventilatory...
Journal Articles
J Exp Biol (2012) 215 (2): 314–323.
Published: 15 January 2012
... decrease branchial ammonia excretion and become ureotelic. The objective of this study was to determine the influences of cortisol and ammonia on ammonia excretion relative to expression of Rhesus (Rh) glycoproteins and the ammonia-fixing enzyme, glutamine synthetase (GS). In vivo infusions...
Includes: Supplementary data
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J Exp Biol (2009) 212 (15): 2394–2402.
Published: 1 August 2009
... cycle (O–UC) enzyme activity and mRNA expression,we subjected toadfish to two-day and seven-day crowding regimes. Plasma cortisol levels were measured and liver tissue was assayed for ammonia and urea concentrations. Liver glutamine synthetase (GS), carbamoyl phosphate synthetase III (CPS), ornithine...
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J Exp Biol (2004) 207 (26): 4605–4614.
Published: 15 December 2004
..., after exposure to air for 17 days, there were significant increases in ammonia content in all these tissues in P. expansa , accompanied by significant increases in glutamine content (2.9-, 2.5-, 4.5- and 3.4-fold,respectively). Simultaneously, there were significant increases in glutamine synthetase...
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J Exp Biol (2003) 206 (14): 2473–2486.
Published: 15 July 2003
... exposure. Instead, ammonia produced through amino acid catabolism was detoxified to glutamine, leading to the accumulation of glutamine in the body during the first 72 h of aerial exposure. Complimenting the increased glutamine formation was a significant increase in glutamine synthetase activity...
Journal Articles
J Exp Biol (2003) 206 (9): 1523–1533.
Published: 1 May 2003
...Patrick J. Walsh; Gregory D. Mayer; Mónica Medina; Matthew L. Bernstein; John F. Barimo; Thomas P. Mommsen SUMMARY We characterized the expression of the nitrogen metabolism enzyme glutamine synthetase [GSase; L-glutamate: ammonia ligase (ADP-forming), E.C. 6.3.1.2] in tissues of the gulf toadfish...
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J Exp Biol (2000) 203 (24): 3703–3715.
Published: 15 December 2000
... N-enrichment of the amide-N in glutamine in the tissues of fish exposed to 15 N-labelled ammonia was virtually the same as that of ammonia-N: i.e. approximately twice that of urea-N in the excreta and the tissues. Glutamine contents and glutamine synthetase activities in the liver and muscle...
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J Exp Biol (1999) 202 (19): 2653–2662.
Published: 1 October 1999
... Atlantic cod ( Gadus morhua ) embryos, CPSase III, ornithine transcarbamoylase (OTCase), glutamine synthetase (GSase) and arginase activities were all expressed prior to hatching. Urea excretion was detected shortly after fertilization and rates were high relative to those of ammonia excretion (50–100...
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J Exp Biol (1999) 202 (3): 237–245.
Published: 1 February 1999
... glutamine content, which peaked at 48 h. The increase in glutamine content could account for the decreases in the amounts of ammonia and urea excretion during air exposure. The specific activities of hepatic glutamate dehydrogenase (amination) and glutamine synthetase in these experimental fish increased...
Journal Articles
J Exp Biol (1998) 201 (16): 2445–2453.
Published: 15 August 1998
... in the sea anemone Aiptasia pulchella , caused by darkness or depletion of the alga Symbiodinium , was partially or completely reversed by supplementing the medium with organic carbon compounds (e.g. α-ketoglutarate). Second, the activity of the ammonium-assimilating enzyme glutamine synthetase...