...Kathy A. Clow; Kenneth J. Rodnick; Tyson J. MacCormack; William R. Driedzic SUMMARY This study investigated the regulation of glucose uptake in Atlantic cod( Gadus morhua ) hearts. Isolated hearts were perfused with or without glucose in the medium, under either normoxic or severely hypoxic...

...Naresh Kumar; Chinmoy S. Dey SUMMARY Sulfonylurea drugs are used in the treatment of type 2 diabetes. The mechanism of action of sulfonylureas is to release insulin from pancreatic cells and they have been proposed to act on insulin-sensitive tissues to enhance glucose uptake. The goal...

...Kenneth J. Rodnick; John R. Bailey; Jenny L. West; Alison Rideout; William R. Driedzic ABSTRACT We investigated the effects of anoxia and contractile activity on glucose uptake and the intracellular location of hexokinase in cardiac muscle of the American eel Anguilla rostrata . Uptake of 2...

... glucose uptake. Sprint-trained rats show elevated maximal HK activity ( Staudte et al . 1973 ), but sprint-trained rainbow trout do not (J. Bryant and E. D. Stevens, unpublished data). Although in vitro HK is inhibited by high G-6-P concentrations ( Sols, 1981 ), and G-6-P levels are high in exercise...