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Keywords: genomics
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Journal Articles
Journal Articles
J Exp Biol (2023) 226 (19): jeb245859.
Published: 12 October 2023
..., such investigations often rely on receptor subtype-specific pharmacological agents (agonists and antagonists; see Glossary) developed and validated in mammals. Meanwhile, evolutionary (phylogenetic and comparative genomic) studies have begun to unravel the diversification of adrenergic receptors (ARs) and reveal...
Journal Articles
J Exp Biol (2020) 223 (24): jeb191262.
Published: 17 December 2020
.... Transcriptomics Metabolomics Genomics RNA-seq Hypothesis testing A goal of comparative physiology is to understand the diverse mechanisms that allow animals to function and survive in their environments. Comparative physiologists (1) inquire vertically across levels of biological organization, (2...
Journal Articles
J Exp Biol (2019) 222 (Suppl_1): jeb191890.
Published: 6 February 2019
..., suggesting an epigenetic control of their migration. The genes and epigenetic changes underpinning migratory behaviour remain largely unknown. The revolution in (epi)genomics and functional genomic tools holds great promise to rapidly move the field of migration genetics forward. Here, we review our current...
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Journal Articles
Journal Articles
J Exp Biol (2015) 218 (1): 114–122.
Published: 1 January 2015
... at a molecular level; however, recent progress on sequencing technology and genome editing tools have begun to blur the lines between model and non-model organisms, opening numerous new avenues for investigation. Here, I review examples of epigenetic phenomena in non-model organisms that have emerged...
Journal Articles
J Exp Biol (2013) 216 (18): 3474–3482.
Published: 15 September 2013
... the paper. COMPETING INTERESTS No competing interests declared. 24 2 2013 17 5 2013 © 2013. Published by The Company of Biologists Ltd 2013 genomics microarrays social evolution nest initiation A common feature of animal societies is social regulation, where...
Includes: Supplementary data
Journal Articles
J Exp Biol (2011) 214 (10): 1773–1782.
Published: 15 May 2011
... is monitoring for changes in their phototactic behavior. In most arthropods, histamine has been shown to play a key role in the visual system. Currently, nothing is known about histaminergic signaling in either D. magna or D. pulex . Here, a combination of immunohistochemistry and genome mining was used...
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Journal Articles
Journal Articles
J Exp Biol (2007) 210 (9): 1497–1506.
Published: 1 May 2007
...Piero Carninci SUMMARY The principal route to understanding the biological significance of the genome sequence comes from discovery and characterization of that portion of the genome that is transcribed into RNA products. We now know that this`transcriptome' is unexpectedly complex and its precise...
Includes: Supplementary data
Journal Articles
J Exp Biol (2007) 210 (9): 1607–1612.
Published: 1 May 2007
...Stuart K. Kim SUMMARY Development of functional genomics tools has made it possible to define the aging process by performing genome-wide scans for transcriptional differences between the young and the old. Global screens for age regulation have been performed for worms and flies, as well as many...
Includes: Supplementary data
Journal Articles
Journal Articles
J Exp Biol (2006) 209 (14): 2660–2677.
Published: 15 July 2006
... Biol . 5 , 355 -366. Cossins, A. R. and Crawford, D. L. ( 2005 ). Fish as models for environmental genomics. Nat. Rev. Genet. 6 , 324 -340. Di Ciano, C., Nie, Z., Szaszi, K., Lewis, A., Uruno, T., Zhan,X., Rotstein, O. D., Mak, A. and Kapus, A. ( 2002 ). Osmotic stress-induced...
Includes: Supplementary data
Journal Articles
J Exp Biol (2004) 207 (15): 2551–2563.
Published: 1 July 2004
... (transmission blocking vaccines), genetic manipulation or chemical incapacitation of the vector. During the past decade, mosquito research has been energized by several breakthroughs, including the successful transformation of anopheline vectors, analysis of gene function by RNAi,genome-wide expression...
Journal Articles
J Exp Biol (2003) 206 (21): 3789–3802.
Published: 1 November 2003
...D. L. Doolan; J. C. Aguiar; W. R. Weiss; A. Sette; P. L. Felgner; D. P. Regis; P. Quinones-Casas; J. R. Yates, III; P. L. Blair; T. L. Richie; S. L. Hoffman; D. J. Carucci SUMMARY Recent advances in the fields of genomics, proteomics and molecular immunology offer tremendous opportunities...
Journal Articles