...-induced oxidative modifications detected in the plasma do not necessarily stem from oxidants produced inside skeletal muscle. Fig. 3. Tissue redox composition at rest. (A) Concentration of free radicals detected by electron paramagnetic resonance (EPR) in rat tissues (Mallard and Kent, 1966...

... © The Company of Biologists Limited 2006 2006 cold exposure antioxidant capacity free radical lipid peroxidation protein carbonyl It is well documented that a hypermetabolic state induced by thyroid hormone administration to experimental animals is accompanied by oxidative stress...

... mitochondrial electron transport chain inhibitors did not produce similar effects. Furthermore, pharmacological inhibition of the mitochondrial permeability transition pore failed to prevent sulfide-induced depolarization. Finally, increased oxidation of the free radical indicators H 2 DCFDA and MitoSOX™...

... are processes regulated by energy metabolism rates and that elevating metabolism will be associated with premature mortality - the rate of living theory. The free-radical theory of ageing provides a potential mechanism that links metabolism to ageing phenomena, since oxygen free radicals are formed...

...Gabriella R. Ramos-Vasconcelos; Marcelo Hermes-Lima SUMMARY The aim of this work was to evaluate the effect of a cycle of estivation and awakening on free radical metabolism in selected organs of the land snail Helix aspersa . Estivation for 20 days induced a 4.9- and 1.8-fold increase in selenium...