... of activation. One hypothesis proposed to account for these force depression (FD) and force enhancement (FE) properties is a change in cross-bridge cycling kinetics. The rate of cross-bridge attachment ( f ) and/or cross-bridge detachment ( g ) may be altered following active shortening and active stretching...

... to eliminate roughly 30% of Ig domain straightening (22 Ig domains of 77 total in rabbit psoas I-band titin; Freiburg et al., 2000 ), which would require PEVK-dependent force generation to occur at shorter SLs when compared with passive stretch at the same SLs. These data resemble residual force enhancement...

... deletion exhibit large deficits in net negative work, suggesting that titin contributes to energy storage and dissipation during stretch–shortening cycles. Energy storage and dissipation Force enhancement Force depression Negative work Muscular dystrophy with myositis Titin/connectin...

... force produced at a given sarcomere length exceeds the predictions of the force–length relationship ( Abbott and Aubert, 1952 ; Edman et al., 1978 ; Edman et al., 1982 ; Morgan, 1994 ; Herzog et al., 2006 ; Leonard and Herzog, 2010 ). This property, termed residual force enhancement, provides...

...). All these studies suggest that upon activation, titin binds calcium at specific locations, thereby increasing its stiffness, and thus its force when stretched. This is a mechanism that could explain residual force enhancement in skeletal muscle contraction ( Herzog et al., 2012c ). However...

... a stretch when recorded from the nerve innervating muscle. The effects of temperature on twitch and tetanic force by direct or indirect stimulation without stretch were also studied as basic data of the stretch experiment. The results from this study suggest that stretch-induced force enhancement in a nerve...

...Daniel R. Peterson; Dilson E. Rassier; Walter Herzog SUMMARY It has been assumed that force enhancement in single fibres of skeletal muscles only occurs on the descending, and not the ascending or plateau region, of the force–length relationship. This assumption has been based, however...

...W. Herzog; T. R. Leonard SUMMARY We investigated force enhancement following stretching in the in situ cat soleus muscle on the ascending and descending limb of the force-length relationship by varying the amount and speed of stretching and the frequency of activation (5 Hz, 30 Hz...