... that granules undergo a dramatic swelling during secretion. Such swelling might be due to an increased osmotic activity of granule contents, following a process of hydration. We hypothesize that this hydration is essential for exocytotic secretion and conclude that cement protein exocytosis is a more complex...

... Physiology, Universität Osnabrück, D-49076 Osnabrück,Germany (e-mail: Weihrauchblues@gmx.net ) 24 9 2004 © The Company of Biologists Limited 2004 2004 ammonia excretion ammonia transporter crab exocytosis Rhesus-like protein Na + /K + -ATPase Ammonia † (i.e. the total...

... into the lumen of the organelle. * Author for correspondence (e-mail: naitoh@pbrc.hawaii.edu ) 18 11 1998 14 01 1998 © The Company of Biologists Limited 1998 contractile vacuole complex cell volume regulation exocytosis electrophysiological parameters V-type proton pump...

... and subsequent omega-figure formation indicated that exocytosis was the major mode of cement secretion. Exocytosis was localized at the apical surface of cement-secreting cells and lasted for over 30 min. Dopamine and noradrenaline also activated the directional transport of secretory granules to the sites...

... is postulated to be due to a localization of high-affinity Ins P 3 receptors. We speculate that in response to cholecystokinin the short-lasting spikes elicit exocytosis from a small ‘available pool’ of vesicles and that the broader oscillations induce both exocytosis and cell changes that involve movement...

... of J H in response (seconds–minutes) to an acid load involves insertion of H + pumps (exocytosis) from a cytosolic pool into the apical membrane. The chronic response (days) to metabolic acid load involves morphological changes (increased apical membrane surface area and number of MR cells). Whole-cell...

... is to understand how brain peptides and neurotransmitters regulate electrical activity (i.e. ionic permeability) of both plasma membrane and intracellular membrane compartments, and how these events are coupled to intracellular biochemistry and Ca 2+ homeostasis and ultimately to exocytosis and hormone release...

...T. J. Rink; D. E. Knight ABSTRACT Many investigators are using numerous preparations for contributing to our present understanding of stimulus-secretion coupling, by which we mean stimulus-dependent exocytosis, sometimes known as the regulated pathway. However, a few model systems have been...

...Dominique Aunis; Marie-France Bader ABSTRACT Chromaffin cells of the adrenal medulla synthesize, store and secrete catecholamines. These cells contain numerous electron-dense secretory granules which discharge their contents into the extracellular space by exocytosis. The subplasmalemmal area...

...John F. Morris; David V. Pow ABSTRACT Although exocytosis is now known to be the universal method by which proteins are released from eukaryotic cells, we know surprisingly little of the mechanism by which exocytosis occurs. One reason for this is that it has proved difficult to capture sufficient...