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Keywords: drug
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Journal Articles
Journal:
Journal of Experimental Biology
J Exp Biol (1996) 199 (7): 1447–1454.
Published: 1 July 1996
... + -ATPase (V-ATPase). Various amphipathic drugs such as local anesthetics and neuron blockers are accumulated in acidic organelles upon energization by proton pumps. However, this process does not require any transporters specific for the drugs: these drugs penetrate through the lipid bilayer against...