... for correspondence ( chris.moyes@queensu.ca ) 3 2 2011 © 2011. 2011 cytochrome oxidase environmental physiology mitochondria muscle temperature One mechanism by which cells fine-tune ATP production in response to persistent changes in energy demand is through changes in mitochondrial...

... ask: what conditions are required at the surface of actively respiring, state III, tightly coupled mitochondria to enhance oxygen flow to cytochrome oxidase? Pigeon heart mitochondria were isolated with minimal damage to the outer mitochondrial membrane and were incubated at low oxygen pressures...

... are shallow, and sarcoplasmic oxygen pressure is nearly the same everywhere. Sarcoplasmic oxygen pressure, buffered near 0.33 kPa (2.5 torr; equivalent to approximately 4 μmol l -1 oxygen) by equilibrium with myoglobin, falls close to the operational K m of cytochrome oxidase for oxygen, and any small...

... 3 4 2002 © The Company of Biologists Limited 2002 2002 hypoxia heart salamander Ambystoma tigrinum cardiac output haematocrit hypometabolism cytochrome oxidase elongation factor 2 representational difference analysis Tiger salamanders ( Ambystoma tigrinum ) inhabit...