...Theanuga Chandrapalan; Raymond W. M. Kwong ABSTRACT Trace metals such as iron, copper, zinc and manganese play essential roles in various biological processes in fish, including development, energy metabolism and immune response. At embryonic stages, fish obtain essential metals primarily from...

... as a major threat to pollinators, metal pollutants, which are often found in complex mixtures, have so far been overlooked. Here, we assessed the impact of acute exposure to field-realistic concentrations of three common metal pollutants, lead, copper and arsenic, and their combinations, on honey bee...

...Lucia Bettedi; Mohamad F. Aslam; Joanna Szular; Konstantinos Mandilaras; Fanis Missirlis Malvolio ( Mvl ) encodes the sole Drosophila melanogaster homologue of divalent metal transporter-1 (DMT1). The Drosophila transporter has been implicated in iron, manganese and copper cellular import. Indeed...

...., Rajaram, R., Seisenbacher,G., Georgiev, O. and Schaffner, W. ( 2007 ). Copper homeostasis in Drosophila by complex interplay of import, storage and behavioral avoidance. EMBO J. 26 , 1035 -1044. Bellingham, S. A., Lahiri, D. K., Maloney, B., La Fontaine, S.,Multhaup, G. and Camakaris, J. ( 2004...

..., and in the nucleus. This study investigated the activation pattern and subcellular distribution of ERK in liver and gill cells of rainbow trout upon hypo-osmotic shock, addition of epidermal growth factor (EGF) and copper treatment. It further set out to characterize the hypothetical role of nuclear-export signal...

...Catherine Gaitanaki; Maria Pliatska; Konstantina Stathopoulou; Isidoros Beis SUMMARY In the present study, we investigated the induction of the p38-MAPK signalling pathway by copper, as exemplified by CuCl 2 , in the isolated perfused heart of the amphibian Rana ridibunda . We found that p38-MAPK...

...Erene Kefaloyianni; Eleni Gourgou; Vanessa Ferle; Efstathios Kotsakis; Catherine Gaitanaki; Isidoros Beis SUMMARY We investigated the effects of various heavy metals such as copper, zinc and cadmium, as well as acute thermal stress, on the signalling mechanisms involved in the protection...

... not significantly affect cHH release and hyperglycemia. In addition, we measured the level and variation of 5-HT in the eyestalk and hemolymph of P. elegans following copper contamination. The release of 5-HT from the eyestalk is very rapid and dose dependent. In the hemolymph, a peak of 5-HT occurs after 30 min...

.... and Ahearn, G. A. ( 2001 ). Copper transport by lobster hepatopancreatic epithelial cells separated by centrifugal elutriation: measurements with the fluorescent dye, Phen Green. J. Exp. Biol. 204 , 1433 -1444. Chavez-Crooker, P., Garrido, N. and Ahearn, G. A. ( 2002 ). Copper transport by lobster...

...M. W. Beaumont; P. J. Butler; E. W. Taylor SUMMARY The present study was undertaken to answer two questions relating to the exposure of brown trout Salmo trutta to sublethal concentrations of copper and low pH (CLP) for 96h. (1) What is the effect of these pollutants on the rate of oxygen...

...Martin Grosell; Chris M. Wood SUMMARY Several components of branchial copper uptake were identified in juvenile freshwater rainbow trout ( Oncorhynchus mykiss ) using 64 Cu. On the basis of competitive interactions between sodium and copper uptake,inhibition of copper uptake by a proton pump...

...Pamela Chavez-Crooker; Nestor Garrido; Gregory A. Ahearn SUMMARY Mechanisms of copper transport into purified mitochondrial suspensions prepared from the hepatopancreas of the Atlantic lobster Homarus americanus were investigated. Mitochondria were purified by combining methods of differential...

...S. J. Clearwater; S. J. Baskin; C. M. Wood; D. G. Mcdonald ABSTRACT A single dose of radioactive copper ( 64 Cu or new Cu) was infused into the stomach of rainbow trout ( Oncorhynchus mykiss ) to model dietary copper (Cu) uptake under conditions of a normal nutritional dose and optimum...

... ) exposed to a sub-lethal combination of copper and low pH. However, this prediction is based upon two assumptions (i) a relatively high membrane permeability for the ammonium ion with respect to that for ammonia gas and (ii) that this is unaltered by exposure to copper and low pH. Since...

... by exposing the fish to waterborne copper (3.2 μmol l −1 ) for 14 days, as indicated by a 38 % increase in cells expressing proliferating cell nuclear antigen (PCNA) relative to controls. The expression of PCNA was most marked in the central area of the filamental epithelium, from where the chloride cells...

... MS-222 anaesthesia and a recovery period of 2 days, the fish were exposed to a 4 day episode of sub-lethal copper levels at pH 5 or kept at control conditions of pH 7 without copper. The copper concentrations had been predetermined by toxicity testing and were approximately 0.47 μ mol l −1 at 5 °C...

... an increase in the number of the gill chloride cells. * Present address: Departament de Biologia, Facultat de Veterinària, Universitat Autónoma de Barcelona, J3ellaterra, Barcelona, Spain. 28 06 1982 13 07 1982 © 1983 by Company of Biologists 1983 Copper zinc chloride...