... compartmentalization drug toxin V-ATPase F-ATPase It is well established that V-ATPases acidify endomembrane systems such as endosomes and lysosomes. The resultant acidic pH is important for a variety of biological reactions, including proteolysis and the invasion of foreign substances (e.g. toxins...

... of Biologists 1988 compartmentalization Paralabrax nebulifer phosphofructokinase red muscle white muscle Regulation of enzymatic activity may entail the reversible association of enzymes with other cellular structures as well as the adjustment of catalytic rates through interactions...