... of differentiation at the site of amputation. The temporal expression pattern of the lncRNA, named Neev, closely resembled the pattern of chitin synthase genes, implicated in chaetae formation. We found that the lncRNA has 49 sites for binding a set of four microRNAs (miRNAs) while the chitin synthase 8 mRNA has 478...

...Gunnar Broehan; Lars Zimoch; Anton Wessels; Beyhan Ertas; Hans Merzendorfer SUMMARY The chitin portion of the peritrophic matrix in the midgut of the tobacco hornworm, Manduca sexta , is produced by chitin synthase 2 (CHS2), a transmembrane family II glycosyltransferase, located at the apical tips...

... the gut epithelium. Insect growth and morphogenesis are strictly dependent on the capability to remodel chitin-containing structures. For this purpose, insects repeatedly produce chitin synthases and chitinolytic enzymes in different tissues. Coordination of chitin synthesis and its degradation requires...