...John O. Onukwufor; Nicole MacDonald; Fred Kibenge; Don Stevens; Collins Kamunde The goal of the present study was to elucidate the modulatory effects of cadmium (Cd) on hypoxia/reoxygenation-induced mitochondrial dysfunction in light of the limited understanding of the mechanisms of multiple...

... channel these contaminants directly to offspring, we exposed parents to aqueous cadmium (Cd) and recorded the subsequent feeding behaviour and Cd content of fry. Fry continued to feed normally from contaminated mucus and accumulated significant tissue concentrations of Cd. In conclusion, this parental...

... functions including mitochondrial metabolism and bioenergetics. In invertebrates, the involvement of NO in bioenergetics and metabolic responses to environmental stress is poorly understood. We determined sensitivity of mitochondrial and cellular respiration to NO and the effects of cadmium (Cd...

... and carbonylation in cadmium-treated haemocytes of mussel Mytilus galloprovincialis . Glutathionylation was detected by western blot analysis and showed actin as its main target. A significant increase of both actin glutathionylation and protein carbonylation, were observed in haemocytes exposed to micromolar...

...Anna V. Ivanina; Anton S. Cherkasov; Inna M. Sokolova SUMMARY Cadmium (Cd) is an important toxicant in estuarine and coastal environments that can strongly affect energy balance of aquatic organisms by increasing the organism's basal energy demand and reducing its aerobic capacity. Mechanisms...

...Anton A. Cherkasov; Robert A. Overton, Jr; Eugene P. Sokolov; Inna M. Sokolova SUMMARY Temperature and heavy metals such as cadmium (Cd) are important environmental stressors that can strongly affect mitochondrial function of marine poikilotherms. In this study, we investigated the combined effects...

...) and supply-side effects (i.e. metabolic capacity to provide ATP to cover the energy demand) of environmental stressors is required. We have studied the effects of temperature (12, 20 and 28°C) and exposure to a trace metal, cadmium (50 μg l –1 ), on the cellular energy budget of a model marine poikilotherm...

...Erene Kefaloyianni; Eleni Gourgou; Vanessa Ferle; Efstathios Kotsakis; Catherine Gaitanaki; Isidoros Beis SUMMARY We investigated the effects of various heavy metals such as copper, zinc and cadmium, as well as acute thermal stress, on the signalling mechanisms involved in the protection...

...I. M. Sokolova; S. Evans; F. M. Hughes SUMMARY Exposure to environmentally prevalent heavy metals such as cadmium can have detrimental effects on a variety of commercially and ecologically important species such as oysters. Since Cd 2+ is known to induce apoptosis in immune cells of vertebrates, we...

...I. M. Sokolova SUMMARY Marine intertidal mollusks, such as oysters, are exposed to multiple stressors in estuaries, including varying environmental temperature and levels of trace metals, which may interactively affect their physiology. In order to understand the combined effects of cadmium...

...Stefanos Dailianis; Martha Kaloyianni SUMMARY The present study investigates the transduction pathway mediated by cadmium in isolated digestive gland cells of mussel Mytilus galloprovincialis . The effects of cadmium treatment on a key glycolytic enzyme, pyruvate kinase (PK), and on Na + /H...

...Heather Rae Hammers Ahearn; Gregory A. Ahearn; Jørgen Gomme ABSTRACT Integumentary uptake of L-[ 3 H]histidine by polychaete worms ( Nereis succinea ) from estuarine waters of Oahu, Hawaii was measured in the presence and absence of calcium and cadmium using a physiological saline that approximated...

... through the system, to describe regulation and homeostasis. This top-down regulation analysis has been used to analyse steady states of energy metabolism in mitochondria, cells and tissues, and to analyse regulation of energy metabolism by cadmium, an external effector, in mitochondria. The combination...

... to normal tapwater. The ionic content of tapwater was (in mmol l −1 ): Ca 2+ , 0·7; Mg 2+ , 0·38; Na + , 0·61; K + , 0·05; Cl − , 0-66; SO 4 2− , 0·32; and HCO 3 − , 315 (pH 7·6). The total calcium content of water was determined with a calcium kit (Sigma Chemical). Water total cadmium content...