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Keywords: amiloride
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Journal Articles
Journal Articles
J Exp Biol (2009) 212 (3): 373–377.
Published: 1 February 2009
... in supplying acid–base equivalents to the respective transporters. Furthermore, any apical processes proposed to be involved in alkali secretion or acid absorption must be Cl – independent and insensitive to DIDS,amiloride, Zn 2+ and ouabain. These results argue against the involvement of putative apical Cl...
Journal Articles
J Exp Biol (2005) 208 (2): 391–407.
Published: 15 January 2005
... (100 μmol l –1 phenamil), 21-fold (10 μmol l –1 CDPC) or 12-fold (2 mmol l –1 amiloride) when Cu o was 800 μmol l –1 compared to those in drug-free controls. Lowering the external chloride concentration [Cl – ] o from 131.6 to 6.6 mmol l –1 (replaced by sodium gluconate) caused the rate of Cu...
Journal Articles
Journal Articles
J Exp Biol (2002) 205 (17): 2705–2713.
Published: 1 September 2002
... to 4.6±0.54 μA cm -2 in preparations adapted to high salinity. The involvement of epithelial Na + channels was determined as current inhibition ( I ami ) by apical application of amiloride; Na + channels were equally active in control epithelia and epithelia from leeches adapted to high salinity. Removal...
Journal Articles
Journal Articles
J Exp Biol (2001) 204 (8): 1509–1517.
Published: 15 April 2001
... integument, none of them mimicked the effect of an experimental rise in intracellular cyclic AMP level. The invertebrate peptides conopressin and angiotensin II amide inhibited short-circuit-current-( I sc ) and amiloride-sensitive Na + transport ( I amil ), although to slightly different degrees...
Journal Articles
J Exp Biol (2000) 203 (14): 2201–2208.
Published: 15 July 2000
... by the blockade of either Na + /H + exchange (using amiloride) or anion transport (using DIDS). The removal of external HCO 3 − and the abolition of outward K + diffusion by the channel blocker Ba 2+ also decreased the rate of proton extrusion following acid load. Depolarization of the cell membrane with 50 mmol...
Journal Articles
Journal Articles
J Exp Biol (1999) 202 (1): 21–32.
Published: 1 January 1999
... and to a three-to fourfold increase in Na + influx. The RVI and the activated Na + influx were blocked by the transport inhibitors amiloride and 4,4′-diisothiocyanatostilbene-2,2′-disulphonic acid (DIDS), both at a concentration of 10 −4 mol l −1 , and the RVI was abolished in a Na + -free saline, indicating...
Journal Articles
J Exp Biol (1997) 200 (23): 3055–3065.
Published: 1 December 1997
...Thomas Cox ABSTRACT The skin of the bullfrog Rana catesbeiana tadpole contains an apical non-selective cation channel that is activated by amiloride. This is in contrast to the adult skin, which has a highly Na + -selective channel that is blocked by amiloride. The purpose of the present study...
Journal Articles
Journal Articles
Journal Articles
J Exp Biol (1995) 198 (5): 1207–1217.
Published: 1 May 1995
... of an induced membrane potential (inside negative; K + /valinomycin). External amiloride (competitive inhibitor; K i =660 μ mol l −1 ) and a monoclonal antibody raised against proteins associated with the lobster ( Homarus americanus ) electrogenic 2Na + /1H + antiporter both inhibited approximately half...
Journal Articles
J Exp Biol (1994) 197 (1): 421–428.
Published: 1 December 1994
... + -pumping V-ATPase, driving secretion of Na + or K + through one or more exchangers, at least one of which is amiloride-sensitive and appears to be closely similar to the Na + /H + exchanger of vertebrates ( Maddrell and O’Donnell, 1992 ). Cl − follows passively, perhaps through apical Cl − channels. Water...
Journal Articles
J Exp Biol (1994) 196 (1): 319–335.
Published: 1 November 1994
... gland coelomosac podocytes and posterior gill epithelial cells – all locations where published reports described unique cation exchange kinetics. Significant fractions of Ca 2+ transport into invertebrate cells across brush-border membranes occurred by an electrogenic, amiloride-sensitive exchange...
Journal Articles
J Exp Biol (1993) 183 (1): 347–352.
Published: 1 October 1993
.... 23 6 1993 © 1993 by Company of Biologists 1993 amiloride toad hydration behavior Bufo punctatus The experiments described here were designed to determine whether the receptors present in amphibian skin are specific to particular solutes, i.e. can toads taste with their skin...
Journal Articles
J Exp Biol (1993) 178 (1): 109–124.
Published: 1 May 1993
... of this experimental approach and an improved technique enabled us to observe pHi regulation even in Cl − -free saline, in contrast to earlier findings. In addition, amiloride (2mmol l − 1) inhibited the maximum rate of pHi recovery by about 80%, SITS (1mmol l − 1) by about 20%. The results strongly suggest...
Journal Articles
J Exp Biol (1992) 172 (1): 417–429.
Published: 1 November 1992
... those that selectively reduce the rate of anion passage lead to secretion of acid fluid. © 1992 by Company of Biologists 1992 V-ATPase insect Malpighian tubules Rhodnius prolixus ion transport fluid transport amiloride furosemide cyclic AMP 5-HT The Malpighian tubules...
Journal Articles
J Exp Biol (1991) 161 (1): 119–134.
Published: 1 November 1991
...Hong Lin; David Randall ABSTRACT Ion transport inhibitors, amiloride, SITS, vanadate and acetazolamide, were added to the water to determine the effect of ion transfer mechanisms on the acidification of water passing over the gills. In neutral water, proton excretion causes a marked reduction...