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Keywords: alternative splicing
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Journal Articles
J Exp Biol (2017) 220 (19): 3508–3518.
Published: 01 October 2017
... hypergravity centrifugation to experimentally manipulate the loads experienced by Drosophila melanogaster . We examined effects of this manipulation on leg muscle alternative splicing of the sarcomere gene troponin T ( Dmel\up ; Fbgn0004169, herein referred to by its synonym TnT ), a process...
Includes: Supplementary data
Journal Articles
J Exp Biol (2016) 219 (9): 1275–1282.
Published: 01 May 2016
.... Alternative splicing Body weight sensing Mechanotransduction Muscle plasticity Scaling Tensegrity The design of most animal locomotor systems appears to be constrained mainly by body weight and associated considerations of durability. The effect of gravity, the one truly constant environmental...
Journal Articles
J Exp Biol (2016) 219 (8): 1249–1258.
Published: 15 April 2016
...Miwa Suzuki; Hitomi Wakui; Takuya Itou; Takao Segawa; Yasuo Inoshima; Ken Maeda; Kiyoshi Kikuchi ABSTRACT This study investigated the expression of aquaporin 2 (AQP2) and its newly found alternatively spliced isoform (alternative AQP2) and the functions of these AQP2 isoforms in the cellular...
Includes: Supplementary data
Journal Articles
J Exp Biol (2014) 217 (10): 1653–1655.
Published: 15 May 2014
... . Transformer Doublesex RNAi Alternative splicing Tribolium Insects are the most diverse group of the animal kingdom. Multiple sex determination mechanisms are found among different insect species. Comparison of these mechanisms suggests the existence of a common downstream regulatory pathway, i.e...
Journal Articles
J Exp Biol (2013) 216 (23): 4454–4461.
Published: 01 December 2013
... (short, medium and long) were identified for the first time that are generated by alternative splicing of downstream coding and non-coding exons. Our work provides the first complete characterisation of the visual pigments of a parrot, perhaps the most colourful order of birds, and moreover suggests more...
Includes: Supplementary data
Journal Articles
J Exp Biol (2011) 214 (9): 1523–1532.
Published: 01 May 2011
...-bearing muscles receive mechanical feedback regarding body weight and consume ATP in order to generate forces sufficient to counteract gravity. Using rats, we examined how variation in body weight affected alternative splicing of fast skeletal muscle troponin T ( Tnnt3 ), a component of the thin filament...
Includes: Supplementary data
Journal Articles
J Exp Biol (2009) 212 (3): 401–412.
Published: 01 February 2009
..., arise by alternative splicing from very similar itp genes. ITP and ITPL are differentially distributed in (1) pars lateralis/retrocerebral complex neurosecretory cells(NSCs) containing both splice forms, (2) interneurons with either one of the splice forms, (3) hindgut-innervating abdominal ITP neurons...
Journal Articles
J Exp Biol (2008) 211 (23): 3653–3660.
Published: 01 December 2008
...James H. Marden; Howard W. Fescemyer; Marjo Saastamoinen; Suzanne P. MacFarland; J. Cristobal Vera; Mikko J. Frilander; Ilkka Hanski SUMMARY A fundamental feature of gene expression in multicellular organisms is the production of distinct transcripts from single genes by alternative splicing...
Journal Articles
J Exp Biol (2007) 210 (19): 3461–3472.
Published: 01 October 2007
... function by generating a large number of mRNA transcripts and protein isoforms from a limited number of genes. The variant transcripts generated by alternative splicing can have changes in coding sequence, premature stop codons or alterations in the 5′ or 3′ UTRs. The effects of alternative splicing vary...
Journal Articles
J Exp Biol (2001) 204 (20): 3457–3470.
Published: 15 October 2001
...James H. Marden; Gail H. Fitzhugh; Mahasweta Girgenrath; Melisande R. Wolf; Stefan Girgenrath SUMMARY The flight muscles of Libellula pulchella dragonflies contain a mixture of six alternatively spliced transcripts of a single troponin T (TnT) gene. Here, we examine how intraspecific variation...