... mechanisms for ionic, osmotic and acid–base regulation, with profound evolutionary and environmental implications; this classic research area continues to evolve as JEB celebrates 100 years of discovery. CO 2 Comparative physiology Gill pH Ionocyte Acidosis Alkalosis National Science...

... stress. pH regulation Alkaline tide Alkalosis Metabolism ATPase Acidosis Triakis semifasciata Energy Acid–base regulation is crucial for all organisms because it prevents homeostatic alterations that would negatively affect essential physiological functions including metabolism...

...K. M. Gilmour; R. M. Euverman; A. J. Esbaugh; L. Kenney; S. F. Chew; Y. K. Ip; S. F. Perry SUMMARY African lungfish Protopterus annectens utilized both respiratory and metabolic compensation to restore arterial pH to control levels following the imposition of a metabolic acidosis or alkalosis. Acid...

...} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \({\dot{M}}_{\mathrm{O}_{2}}\) \end{document} ) and elevation in secretion P CO 2 effects, which peaked at 2 h and attenuated by 3.5-4 h. Secretion was inhibited by acidosis and stimulated by alkalosis...

...Konstantina Stathopoulou; Catherine Gaitanaki; Isidoros Beis SUMMARY We investigated the activation of the p38-MAPK signalling pathway during extracellular pH changes in the isolated perfused amphibian heart. Extracellular alkalosis (pH 8.5 or 9.5) maximally activated p38-MAPK within 2 min (4.17...

... 12 2005 © The Company of Biologists Limited 2006 2006 fish dogfish Squalus acanthias gill acid base regulation H + -ATPase base infusion alkalosis colchicine basolateral H + -ATPase microtubule vesicular trafficking. The gills of marine elasmobranchs account for over...

... H + -ATPase Na + /K + -ATPase NHE acid infusion base infusion alkalosis acidosis The gills of marine elasmobranchs are an excellent model for studying the acid-base regulatory mechanism of fishes. While they are the principal acid-base regulatory organs ( Heisler,1988 ), they also have...