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Keywords: ageing
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Journal Articles
J Exp Biol (2021) 224 (12): jeb242465.
Published: 18 June 2021
.... Ageing Life history Telomeres Trade-offs Yellow-legged gull Telomeres are terminal DNA–protein complexes placed at end of linear chromosomes that play a key role in preventing genome degradation ( O'Sullivan and Karlseder, 2010 ). Although there are some exceptions, telomeres decrease...
Includes: Supplementary data
Journal Articles
J Exp Biol (2021) 224 (10): jeb242172.
Published: 24 May 2021
...Geoffrey A. Power; Sean Crooks; Jared R. Fletcher; Brian R. Macintosh; Walter Herzog ABSTRACT We investigated age-related changes to fascicle length, sarcomere length and serial sarcomere number (SSN), and how this affects passive force. Following mechanical testing to determine passive force...
Journal Articles
J Exp Biol (2021) 224 (1): jeb231290.
Published: 06 January 2021
... future performance. Ageing Bird Developmental mismatch Fitness Hatching asynchrony Maternal allocation Early-life conditions (i.e. conditions experienced during development) can have long-lasting effects on behavior ( Weinstock, 2008 ), physiology ( Sheriff et al., 2010 ) and fitness...
Journal Articles
J Exp Biol (2020) 223 (23): jeb230185.
Published: 02 December 2020
...Andrew W. McCracken; Eleanor Buckle; Mirre J. P. Simons ABSTRACT Dietary restriction (DR) is a key focus in ageing research. Specific conditions and genotypes were recently found to negate lifespan extension by DR, questioning its universal relevance. However, the concept of dietary reaction norms...
Includes: Supplementary data
Journal Articles
J Exp Biol (2020) 223 (11): jeb224063.
Published: 04 June 2020
... with different maximum lifespan potential (MLSP) and the longer-lived outgroup species Aphyosemion australe were studied to test whether they conform to the predictions of the longevity–homeoviscous adaptation (LHA) theory of ageing. Lipid analyses were performed in whole-fish samples and the peroxidation index...
Includes: Supplementary data
Journal Articles
J Exp Biol (2020) 223 (2): jeb213785.
Published: 28 January 2020
... to the clearance of a broad spectrum of exogenous and endogenous toxicants and harmful metabolites, including the reactive lipid aldehyde byproducts of lipid peroxidation that are a hallmark of cellular ageing. Here, we tested whether declining transporter functionality may contribute to functional decline...
Journal Articles
J Exp Biol (2019) 222 (24): jeb216176.
Published: 18 December 2019
... stressor affects early postnatal telomere length, linking prenatal conditions to future fitness. Ageing Predation risk Stressors Yellow-legged gull Across taxa, evidence indicates that conditions during embryo development can exert long-term effects on important life-history traits...
Includes: Supplementary data
Journal Articles
J Exp Biol (2019) 222 (24): jeb207043.
Published: 16 December 2019
... stress theory of ageing ( Beckman and Ames, 1998 ) that was originally proposed as the free radical theory of ageing ( Harman, 1956 ). A variation of this theory, the membrane pacemaker theory of ageing ( Hulbert, 2005 ), emphasises the role of PUFA and membrane lipid peroxidation in free radical damage...
Includes: Supplementary data
Journal Articles
J Exp Biol (2018) 221 (15): jeb181586.
Published: 10 August 2018
... at chromosome ends that shorten with age. At the cellular level, telomeres maintain chromosome stability ( Blackburn, 1991 ), and, at the organismal level, telomere length predicts individual variation in lifespan across taxa ( Heidinger et al., 2012 ; Boonekamp et al., 2013 ; Bauch et al., 2014 ; Wilbourn...
Journal Articles
J Exp Biol (2018) 221 (13): jeb163840.
Published: 06 July 2018
... produced per muscle mass. Obesity and ageing have similar physiological consequences. The synergistic effects of obesity and ageing on muscle function may exacerbate morbidity and mortality. Important future research directions include determining: the relationship between time course of weight gain...
Journal Articles
J Exp Biol (2013) 216 (15): 2879–2888.
Published: 01 August 2013
.... The physiological constraints that limit investment in both reproduction and lifespan are not well understood and stir ongoing debate. One aspect of physiology that has been implicated in ageing for 50 years is oxidative stress ( Harman, 1956 ; Beckman and Ames, 1998 ), which occurs when there is an imbalance...
Includes: Supplementary data
Journal Articles
J Exp Biol (2013) 216 (8): 1388–1397.
Published: 15 April 2013
... of the Glanville fritillary butterfly ( Melitaea cinxia ). Measurements of MR peak showed significant repeatability. Senescence occurred only shortly before death. RMR showed a U-shaped relationship with age and very low repeatability. Intraspecific association between metabolic rates and lifespan was tested under...
Includes: Supplementary data
Journal Articles
J Exp Biol (2013) 216 (3): 492–501.
Published: 01 February 2013
...Ben Mulcahy; Lindy Holden-Dye; Vincent O'Connor SUMMARY Frailty is a feature of neuromuscular ageing. Here we provide insight into the relative contribution of pre- and postsynaptic dysfunction to neuromuscular ageing using the nematode Caenorhabditis elegans . Assays of C. elegans motility...
Journal Articles
J Exp Biol (2012) 215 (7): 1076–1083.
Published: 01 April 2012
...Andreas Behrends; Ricarda Scheiner SUMMARY Honey bees ( Apis mellifera ) are well known for their excellent learning abilities. Although most age groups learn quickly to associate an odor with a sucrose reward, newly emerged bees and old foragers often perform poorly. For a long time, the reason...
Journal Articles
J Exp Biol (2011) 214 (4): 599–606.
Published: 15 February 2011
..., the Ott-Ahlqvist equation was applied. This equation can formulate the effects of multiple serum proteins on COP, according to their molecular mass. The COP values determined in chickens were lower than those previously found in mammals. COP s increased with age in males, and was higher in adult males...
Journal Articles
J Exp Biol (2008) 211 (15): 2492–2501.
Published: 01 August 2008
...Eva E. R. Philipp; Maike Schmidt; Carina Gsottbauer; Alexandra M. Sänger; Doris Abele SUMMARY The decline of cellular and especially mitochondrial functions with age is,among other causes, held responsible for a decrease in physiological fitness and exercise capacity during lifetime. We...
Journal Articles
J Exp Biol (2007) 210 (19): 3407–3414.
Published: 01 October 2007
...Børge Moe; Frédéric Angelier; Claus Bech; Olivier Chastel SUMMARY Ageing is associated with a decline in basal metabolic rate (BMR) in many species, including humans. The evolutionary and physiological causes underlying the relationship between age and BMR are poorly understood. Studies...
Journal Articles
J Exp Biol (2005) 208 (9): 1717–1730.
Published: 01 May 2005
... of body mass(exponent between -0.08 and 0.08). This means that across species a gram of tissue on average expends about the same amount of energy before it dies regardless of whether that tissue is located in a shrew, a cow, an elephant or a whale. This fact led to the notion that ageing and lifespan...
Journal Articles
J Exp Biol (1990) 153 (1): 105–127.
Published: 01 October 1990
...H. L. ATWOOD; C.K. GOVIND Adaptation of neural systems to altered activity and age often involves recruitment, inactivation or modification of synapses. Crustacean motor systems are amenable to experimental investigation of these processes. They possess large identifiable neurones that can...