... be especially fruitful to uncover mechanisms regulating total blood cell numbers across development and ageing. Authors for correspondence ( [email protected] ; [email protected] ) Competing interests The authors declare no competing or financial interests. 4 10 2024 18...

...Judith Korb ABSTRACT Social insects (termites, ants and some bees and wasps) are emerging model organisms of ageing research. In this Commentary, I outline which advantages they offer compared with other organisms. These include the co-occurrence of extraordinarily long-lived, highly fecund queens...

...Bin-Yan Hsu; Nina Cossin-Sevrin; Antoine Stier; Suvi Ruuskanen ABSTRACT The early-life environment is known to affect later-life health and disease, which could be mediated by the early-life programming of telomere length, a key hallmark of ageing. According to the fetal programming of telomere...

...Christian König; Bertram Gerber ABSTRACT Memory scores are dynamic across developmental stages. In particular, memory scores typically decrease from late adolescence into old age, reflecting complex changes in mnemonic and sensory-motor faculties, metabolic and motivational changes, and changes...

... length. (A) Initial and final SEMs of causal effects between the change in body mass, telomerase activity and telomere length between hatching day and 30 days of age. The dashed grey arrows represent statistically non-significant correlations and the black solid arrows denote significant correlations...

...Geoffrey A. Power; Sean Crooks; Jared R. Fletcher; Brian R. Macintosh; Walter Herzog ABSTRACT We investigated age-related changes to fascicle length, sarcomere length and serial sarcomere number (SSN), and how this affects passive force. Following mechanical testing to determine passive force...

... development and fitness in birds and mammals . Trends Ecol. Evol. 14 , 343 - 348 . 10.1016/S0169-5347(99)01639-0 López-Otín , C. , Blasco , M. A. , Partridge , L. , Serrano , M. and Kroemer , G. ( 2013 ). The hallmarks of aging . Cell 153 , 1194 - 1217 . 10.1016...

...Andrew W. McCracken; Eleanor Buckle; Mirre J. P. Simons ABSTRACT Dietary restriction (DR) is a key focus in ageing research. Specific conditions and genotypes were recently found to negate lifespan extension by DR, questioning its universal relevance. However, the concept of dietary reaction norms...

... with different maximum lifespan potential (MLSP) and the longer-lived outgroup species Aphyosemion australe were studied to test whether they conform to the predictions of the longevity–homeoviscous adaptation (LHA) theory of ageing. Lipid analyses were performed in whole-fish samples and the peroxidation index...

... to the clearance of a broad spectrum of exogenous and endogenous toxicants and harmful metabolites, including the reactive lipid aldehyde byproducts of lipid peroxidation that are a hallmark of cellular ageing. Here, we tested whether declining transporter functionality may contribute to functional decline...

... telomere biology: a contributory and interactive factor in aging, disease risks, and protection . Science   350 , 1193 - 1198 . 10.1126/science.aab3389 Blasco , M. A. ( 2007 ). The epigenetic regulation of mammalian telomeres . Nature Rev. Gen.   8 , 299 - 309 . 10.1038/nrg2047...

... be partially explained by oxidative damage as a result of the diet-induced increase in membrane polyunsaturated fatty acids in workers. Social insect Ageing Plasmalogens Membrane peroxidation index Membrane phospholipids Polyunsaturated fatty acids Apis mellifera Social insects represent...

...-1-1/ Highlighted Article: Faster embryonic growth rate, manipulated using incubation temperature, results in shorter telomere length at hatching in a wild bird species, the common tern. Ageing Embryonic development Cell division Life-history trade-off Lifespan Senescence...

... produced per muscle mass. Obesity and ageing have similar physiological consequences. The synergistic effects of obesity and ageing on muscle function may exacerbate morbidity and mortality. Important future research directions include determining: the relationship between time course of weight gain...

... groups did not differ in age at the start of the experiment (normal food: controls=112±8 days old; large litter=110±10 days; small litter 110±10 days; custom food: controls=109±8 days; large litter=98±7 days; small litter=104±10 days; difference between groups: F 2,53 =0.26, P =0.78; difference...

... of the Glanville fritillary butterfly ( Melitaea cinxia ). Measurements of MR peak showed significant repeatability. Senescence occurred only shortly before death. RMR showed a U-shaped relationship with age and very low repeatability. Intraspecific association between metabolic rates and lifespan was tested under...

...Ben Mulcahy; Lindy Holden-Dye; Vincent O'Connor SUMMARY Frailty is a feature of neuromuscular ageing. Here we provide insight into the relative contribution of pre- and postsynaptic dysfunction to neuromuscular ageing using the nematode Caenorhabditis elegans . Assays of C. elegans motility...

...Andreas Behrends; Ricarda Scheiner SUMMARY Honey bees ( Apis mellifera ) are well known for their excellent learning abilities. Although most age groups learn quickly to associate an odor with a sucrose reward, newly emerged bees and old foragers often perform poorly. For a long time, the reason...

..., the Ott-Ahlqvist equation was applied. This equation can formulate the effects of multiple serum proteins on COP, according to their molecular mass. The COP values determined in chickens were lower than those previously found in mammals. COP s increased with age in males, and was higher in adult males...

...Eva E. R. Philipp; Maike Schmidt; Carina Gsottbauer; Alexandra M. Sänger; Doris Abele SUMMARY The decline of cellular and especially mitochondrial functions with age is,among other causes, held responsible for a decrease in physiological fitness and exercise capacity during lifetime. We...