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In collection:Cardiology articles
J Exp Biol (2021) 224 (16): jeb242778.
Published: 24 August 2021
... preparations from Burmese pythons. We located the dominant pacemaker site at the base of the right leaflet of the sinoatrial valve (SAV), but latent pacemakers were also identified in a circular region around the SAV. Acetylcholine (10 −5 mol l −1 ) or noradrenaline (10 −6 mol l −1 ) induced shifts...
J Exp Biol (2017) 220 (8): 1405–1410.
Published: 15 April 2017
..., we expanded the toolbox for the identification of cholinergic neurons by generating a new line FRT-STOP-FRT-VAChT::HA that is a conditional tagged knock-in of the vesicular acetylcholine transporter ( VAChT ) gene in its endogenous locus. Importantly, in comparison to already available tools...
J Exp Biol (2015) 218 (11): 1777–1786.
Published: 1 June 2015
... acetylcholine (ACh), an acute bout of hypoxia (15 mmHg) increased the time engaged in ASR by 5.5 and 4.9 times, respectively, compared with controls. Larvae previously immersed in 10 μmol l −1 5-HT or ACh also displayed an increased ASR response. Our results support the notion that ASR is a behavioural response...
J Exp Biol (2014) 217 (10): 1745–1751.
Published: 15 May 2014
... no competing financial interests. 16 10 2013 4 2 2014 © 2014. Published by The Company of Biologists Ltd 2014 Acetylcholine Muscarinic receptors Fish heart Atrial myocytes Ionic currents I KACh Cardiac contractility is adjusted to circulatory demands on a beat-to-beat...
J Exp Biol (2013) 216 (13): 2442–2450.
Published: 1 July 2013
... through a variety of receptors and their action has been implicated in processes such as attention, learning and memory, aggression, reproductive behaviour and state-dependent mechanisms. Here, we review recent work on neuromodulation of electrosensory processing by acetylcholine and serotonin...
J Exp Biol (2013) 216 (10): 1799–1807.
Published: 15 May 2013
... by a UK government Insect Pollinators Initiative (BBSRC, NERC, Wellcome Trust, DEFRA, and the Scottish Government) [grant no. BB/I000143/1 to G.A.W.]. Deposited in PMC for release after 6 months. ACh acetylcholine AChE acetylcholinesterase CS conditioned stimulus LTM long-term...
Includes: Supplementary data
J Exp Biol (2012) 215 (12): 2108–2116.
Published: 15 June 2012
...Daniel Kueh; John A. Jellies SUMMARY The heart excitor (HE) motor neuron in the leech Hirudo releases acetylcholine (ACh) and a peptide, FMRFamide, to regulate the contractile activity of the heart tube and associated side vessels. Consistent with Dale's principle, it was assumed that both...
J Exp Biol (2009) 212 (22): 3605–3611.
Published: 15 November 2009
... ) 20 8 2009 2009 crayfish acetylcholine octopamine excitation inhibition motor pattern Effective behaviors require that activities of different parts of an animal's nervous system be integrated. This necessary coordination can be achieved by activation of particular neural...
J Exp Biol (2008) 211 (23): 3703–3711.
Published: 1 December 2008
... the nature of the quiescent state and the basis for spontaneous switching between swimming and quiescence. The transition from swimming to quiescence is promoted by acetylcholine signaling and initially during quiescence body wall muscles are in a state of contraction. After the first minute, quiescent worms...
Includes: Multimedia, Supplementary data
J Exp Biol (2008) 211 (14): 2346–2357.
Published: 15 July 2008
... locusts, fictive flight was initiated by bath application of the muscarinic agonist pilocarpine, the acetylcholine analogue carbachol, and the acetylcholinesterase blocker eserine, but not by nicotine. Furthermore, in addition to octopamine, various other amines including dopamine, tyramine and histamine...
J Exp Biol (2006) 209 (6): 1093–1100.
Published: 15 March 2006
... acetylcholine sympatho-vagal balance heart rate variability zebrafish Danio rerio © The Company of Biologists Limited 2006 2006 23 1 2006 * Author for correspondence (e-mail: email@example.com ) References Altimiras, J. ( 1999 ). Understanding autonomic...
J Exp Biol (2004) 207 (23): 4085–4094.
Published: 1 November 2004
... time we show that the regular propagating anterograde waves that occur in the zebrafish larval gut before and around the onset [at 5–6 days post fertilization (d.p.f.)] of feeding are modulated by acetylcholine or atropine, PACAP and NKA (neurokinin A). At 3 d.p.f., when no spontaneous motility has...
J Exp Biol (2004) 207 (11): 1759–1769.
Published: 1 May 2004
... skin preparations with acetylcholine (ACh) (20 μmol l -1 ) and muscarine (30 μmol l -1 ) but not nicotine (up to 50 mmol l -1 ), suggesting that cholinergic muscarinic receptors are involved. Changing the osmolarity of the external solution had no effect on spectral reflectivity. To study...
M. J. Brierley, A. J. Ashworth, T. P. Craven, M. Woodburn, J. R. Banks, W. Lu, D. Riccardi, R. J. Balment, C. R. McCrohan
J Exp Biol (2003) 206 (22): 4011–4020.
Published: 15 November 2003
... for 30-60 min before recording. In a preliminary study, Brierley et al.( 2000 ) observed both depolarising and hyperpolarising responses to acetylcholine in Dahlgren cells and, in a subset of cells, no response at all. In this study, superfusion with ACh (100 μmol l -1 ) elicited similar...
J Exp Biol (2002) 205 (6): 799–806.
Published: 15 March 2002
... , in order to see whether or not they share common mechanisms. Luminescence induced by general depolarisation of tissues using KCl (200 mmol l –1 ) shows different patterns, according to species. Only A. filiformis emits light in response to acetylcholine. In this species, the involvement of both muscarinic...
Maria Umberta Delmonte Corrado, Huguette Politi, Marzia Ognibene, Cristiano Angelini, Francesca Trielli, Patrizia Ballarini, Carla Falugi
J Exp Biol (2001) 204 (11): 1901–1907.
Published: 1 June 2001
...: the neurotransmitter acetylcholine (ACh), both its nicotinic and muscarinic receptors and its lytic enzyme acetylcholinesterase (AChE). Our results on the inhibition of mating-cell pairing in vivo in mating-competent cells treated with cholinomimetic drugs support the hypothesis that the cholinergic system plays...
J Exp Biol (1992) 170 (1): 203–233.
Published: 1 September 1992
... to these somata. The response to acetylcholine is mainly nicotinic but contains a small muscarinic component. 2. The nicotinic (ACh1) response is a rapid depolarisation accompanied by a decrease in membrane resistance. In voltage-clamped somata, the current mediating the ACh1 response is inward over the membrane...
J Exp Biol (1991) 157 (1): 101–122.
Published: 1 May 1991
... putative transmitters were examined by perfusion of the gland and two promising candidates were selected for detailed analysis. 2. Acetylcholine (ACh) was the only substance tested which excited the gland cells. It produced a large, Na + -dependent depolarization that elicited 1–3 action potentials...
J Exp Biol (1991) 155 (1): 415–433.
Published: 1 January 1991
... retractor. Physiological and pharmacological analyses suggested that the principal excitatory transmitter of B4 at the neuromuscular junctions was acetylcholine (ACh), although glutamate and aspartate also elicited the contraction. A pair of cerebral ganglion cells, v-RCDN and v-LCDN, was found to have...
J Exp Biol (1990) 148 (1): 201–219.
Published: 1 January 1990
... peptides known from Helix , accounted for most of the immunoreactivity. Parallel radioimmunoassay (RIA) also showed that FMRFamide predominates in the C3 neurone. The nicotinic acetylcholine (ACh) receptor antagonists benzoquinonium (10 −5 moll −1 ) and trimetaphan (5 × 10 −5 moll −1 ) reversibly reduced...