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Keywords: VEGF
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Journal Articles
Journal Articles
J Exp Biol (2004) 207 (18): 3233–3242.
Published: 15 August 2004
... governed by the activation of hypoxia-inducible transcription factors (HIF-1, HIF-2), which in turn modulate expression of hypoxically regulated genes such as those encoding vascular endothelial growth factor ( VEGF ) and erythropoietin( EPO ). EPO is a glycoprotein that is produced mainly by interstitial...
Journal Articles
J Exp Biol (2004) 207 (18): 3171–3188.
Published: 15 August 2004
... lateral sclerosis (ALS; Cluskey and Ramsden, 2001 ; Rakhit et al., 2002 ). A novel player in the aetiology of ALS has only recently been identified. To study the relevance of HIF-mediated induction of the VEGF-gene, transgenic mice with the hypoxia-responsive element (HRE) deleted were generated...