... bee species upon unfolded protein response (UPR) activation, suggesting that stress-induced regulation of cellular methylation reactions is a common feature of bees. Therefore, this study suggests that the honey bee can serve as an important model for bee biology more broadly, although studies...

... is to maintain good proteostasis via the unfolded protein response (UPR) ( Hetz et al., 2015 ). The two primary components of the UPR are (1) the ubiquitin–proteasome system, which limits the accumulation of damaged proteins by degrading denatured non-functional proteins and preventing their accumulations from...

... cellular signalling pathways [hypoxia inducible factor (HIF), unfolded protein response (UPR) and mTOR pathways] since most of what we know comes from studies on cancerous mammalian cell lines. Arctic char were exposed to cumulative graded hypoxia trials for 3 h at four air saturation levels (100%, 50%, 30...