... for the plasma membrane calcium channels, TRP and TRPL (MacPherson et al., 2000 , 2001 ). Thus,CAP 2b -induced calcium signalling occurs via multichannel mechanisms. We demonstrate here that IP 3 R plays a role in CAP 2b -induced calcium signalling( Fig. 5 ). Extensive work using norpA mutants has shown...

... bioassay, we show that three tachykinin-related peptides (TRPs),leucokinin I, serotonin (5-HT), octopamine, the cardioacceleratory peptides 1a, 1b and 2c, cGMP and cAMP each cause an increase in the rate of fluid secretion in pharate adult tubules. Whereas the possible hormonal sources of biogenic amines...

... (InsP 3 ) and diacyl glycerol (DAG), leading to activation of two classes of Ca 2+ -permeable light-sensitive channel, encoded by the trp and trpl genes. In some invertebrate photoreceptors, excitation is mediated by release of Ca 2+ from intracellular stores by InsP 3 ; however, in Drosophila...