.... and Weihrauch , D. ( 2015 ). Mechanism of ammonia excretion in the freshwater leech Nephelopsis obscura: characterization of a primitive Rh protein and effects of high environmental ammonia . Am. J. Physiol. Regul. Integr. Comp. Physiol.   309 , R692 - R705 . 10.1152/ajpregu.00482.2014 Shartau...

... Highlighted Article: Elasmobranchs, which are nitrogen-limited in nature, take up the toxicant ammonia across their gills from environmentally realistic levels in seawater, using it to make urea, an essential osmolyte. Elasmobranch Urea Ornithine–urea cycle Rh proteins Methylamine Glutamine...

... whether compensatory changes in the ammonia transporting proteins might be contributing to sustaining J net,amm under conditions of reduced functional lamellar surface area, the relative expression and branchial distribution of four Rh proteins were assessed by western blotting and immunocytochemistry...

... with the cloning of Rh glycoprotein gene(s) could shed light on the role that these proteins play in these primitive fishes. The imminent release of the full lamprey genome should give researchers the opportunity to mine the genome for not only Rh proteins, but other proteins involved in ammonia transport...