...), and cortisol treatment significantly increased transepithelial resistance (TER) and decreased paracellular [ 3 H]PEG-4000 flux. Epithelial permeability was unaffected by deoxycorticosterone or aldosterone. The GR antagonist RU486 as well as MR antagonists spironolactone and RU26752 significantly reduced...

... containing either cortisol (110 mg kg –1 fish), or cortisol plus the glucocorticoid receptor antagonist RU486 (mifepristone; 1100 mg kg –1 fish), and sampled after 5 days of social interactions with either a similar sized (<1.5% difference in fork length)or smaller conspecific (>5% difference). Within...

... RU486 and spironolactone. RU486 is a potent antagonist of the glucocorticoid actions of cortisol, whereas spironolactone exhibits high-affinity binding to mineralocorticoid receptors, with a resulting blockade of mineralocorticoid properties in mammals. Untreated rainbow trout, as well as rainbow trout...