... of protein metabolism. These metabolic perturbations are abated after 10 days and disappear after 1 month of cyclic hypoxia, while fish globally maintain their growth. We also found a decrease of the succinate:fumarate ratio following a month of acclimation, which suggests a mechanism to prevent ROS...

... hyperthermic death. We consider in this Commentary how loss of mitochondrial cristae structure is a principal contributor to mitochondrial failure. Mitochondria Temperature Hyperthermic death ATP Proton motive force Leak respiration Proton gradient Cristae Ultrastructure ROS The Marsden...

... Plasticity ROS Energetics Natural Sciences and Engineering Research Council of Canada http://dx.doi.org/10.13039/501100000038 Queen Elizabeth II Graduate Scholarship in Science and Technology Western University http://dx.doi.org/10.13039/501100004381...

... to cold promotes mitochondrial metabolism, resulting in better mitochondrial respiration. UCP HSP Bioenergetics ROS Insect Gromphadorhina coquereliana Narodowe Centrum Nauki http://dx.doi.org/10.13039/501100004281 2017/24/C/NZ4/00228 Because temperate and polar species...

... that disturbances in gill permeability and transport functions during air exposure were minimal. The neutralization of the ROS generated during the air and recovery exposures was sufficiently efficient to prevent damage to the other organs. This is not always the case. Lima et al. (2015) found increases...

...Brittney G. Borowiec; Graham R. Scott ABSTRACT Hypoxia is common in aquatic environments, and exposure to hypoxia followed by re-oxygenation is often believed to induce oxidative stress. However, there have been relatively few studies of reactive oxygen species (ROS) homeostasis and oxidative...

... ) by examining covariation in VTG with the ovarian cycle, and relative to reactive oxygen species (ROS) including baseline superoxide (bSO). Plasma VTG decreased prior to ovulation, when VTG is deposited into follicles. VTG, however, remained elevated post-ovulation when no longer necessary for yolk provisioning...

...Kenneth R. Olson ABSTRACT The biological effects of oxidants, especially reactive oxygen species (ROS), include signaling functions (oxidative eustress), initiation of measures to reduce elevated ROS (oxidative stress), and a cascade of pathophysiological events that accompany excessive ROS...

...Gigi Y. Lau; Jeffrey G. Richards ABSTRACT Environmental hypoxia presents a metabolic challenge for animals because it inhibits mitochondrial respiration and can lead to the generation of reactive oxygen species (ROS). We investigated the interplay between O 2 use for aerobic respiration and ROS...

... ). ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis . Nat. Rev. Mol. Cell Biol.   8 , 813 . 10.1038/nrm2256 Del Rey , M. J. , Valín , A. , Usategui , A. , García-Herrero , C. M. , Sánchez-Aragó , M. , Cuezva , J. M. , Galindo , M...

... was enhanced by high-salt exposure in YSM tissue. Moreover, the reduction in expression of HIF2 and FGF2 genes might cause high-salt-suppressed angiogenesis. Interestingly, we show that high-salt exposure causes excess generation of reactive oxygen species (ROS) in the heart and YSM tissues, which could...

... acute thermal shifts. We measured the mitochondrial respiration rate ( V̇ O 2 ) through multiple complexes of the electron transport system following thermal acclimation (to 5, 15, 33°C) and assessed maintenance of mitochondrial membrane potential (Δ p ) and rates of reactive oxygen species (ROS...

... species (ROS) in disused muscles may lead to oxidative stress, which in turn is associated with increased atrophic or apoptotic signalling and/or oxidative damage to the muscle and thus muscle disuse atrophy. Increases in the rate of oxygen consumption likely increase the overall generation of ROS in vivo...

... oxidation of lipids `lipidperoxidation' commences with lipid radical production and leads to the accumulation of stable degradation products, such as malondialdehyde ( Sies,1986 ). During exercise elevated metabolic rates can lead to higher ROS generation and thus higher lipidperoxidation. However...

.../recovery. Our data suggest that p38 MAPK inhibits ERK activity at the level of MEK during chemical anoxia. During recovery, we demonstrated the requirement for ROS, produced via a NAD(P)H oxidase-like activity for reactivation of ERK in a Raf-independent manner. We speculate that ROS results...

... of membrane potential and radical production. Acclimatisation of lugworms to pre-spawning/summer conditions is associated with rising mitochondrial substrate oxidation rates, higher proton leakage rates, elevated membrane potentials, and increased production of reactive oxygen species (ROS)in isolated...