... for correspondence (e-mail: [email protected] ) 24 12 2007 © The Company of Biologists Limited 2008 2008 malaria mosquito Plasmodium Anopheles aging insulin oxidative stress antioxidant Malaria is responsible for over 1 million deaths worldwide each year( Guinovart et al...

... and because the Plasmodium parasite is a complex multistage pathogen targeted by multiple immune responses. Sterile protective immunity can be achieved by immunization with radiation-attenuated sporozoites, and anti-disease immunity can be induced in residents in malaria-endemic areas. However, the 23 Mb...

... a refractory mosquito. Accomplishments include germline transformation of several important mosquito vectors, the completed genomes of the mosquito Anopheles gambiae and the malaria parasite Plasmodium falciparum , and the identification of promoters and effector genes that confer resistance in the mosquito...