... debated. The ‘membrane pacemaker’ hypothesis of metabolism and of aging, respectively, suggest that increased lipid unsaturation and large amounts of polyunsaturated fatty acids (PUFAs) in cell membranes increase the cellular metabolic rate as well as the vulnerability of the cell to oxidative damage...

... induced changes in the expression of neuropeptides implicated in the control of food intake through a mechanism not involving central fatty acid-sensing systems. Food intake Larval fish PUFA Lipid sensing Neuropeptides Cocaine- and amphetamine-related transcript In previous studies, we...

...Victoria Diedrich; Stephan Steinlechner; Frank Scherbarth Essential polyunsaturated fatty acids (PUFA) have been shown to play a beneficial role in hibernating mammals. High amounts of dietary PUFA led to an earlier hibernation onset, deeper and longer hibernation bouts and a higher proportion...

... under conditions of low ATP turnover (state 4). * Author for correspondence (e-mail: [email protected] ) 15 6 2008 © The Company of Biologists Limited 2008 2008 hibernation proton leak mitochondria polyunsaturated fatty acid PUFA oxidative phosphorylation oxidative...