... to dissect structure/function relationships in several P-type ATPases by means of site-directed mutagenesis. This paper reviews three phenotypically distinct classes of mutant that have resulted from work on the yeast PMA1 H + -ATPase: (1) mutant ATPases that are poorly folded and retained in the endoplasmic...

... of Biologists 2000 membrane transport protein crystallization P-type ATPase proton pump structure conformational change molecular dynamics Ion-translocating ATPases are essential cellular energy converters that transduce the chemical energy of ATP hydrolysis into transmembrane ionic...

.... terraenovae than in S. exigua . Vanadate sensitivity suggested that both insects possess P-type ATPases. The K + activity gradient in P. terraenovae muscles was also found to be ouabain-sensitive, indicating the involvement of a Na + /K + -ATPase. In contrast, the K + gradient in S. exigua muscles proved...