... during the spawning period has a nutritional programming effect in offspring of gilthead seabream and affects long-term metabolism. Studies showed modulation of genes such as fads2 , which is considered to be a rate-limiting step in the synthesis of n -3 long-chain polyunsaturated fatty acids ( n -3 LC...

... methylation reactions including DNA and histone methylation. As such, it represents a potential critical factor in nutritional programming. Here, we investigated whether early methionine restriction at first feeding could have long-term programmed metabolic consequences in rainbow trout. For this purpose...

... to the non-inhibition of the last step of gluconeogenesis and thus to establishing the glucose-intolerant phenotype in trout fed a high-carbohydrate diet as early as first feeding. This information is crucial for nutritional programming investigations as it suggests that first feeding would be too late...

...I. Geurden; J. Mennigen; E. Plagnes-Juan; V. Veron; T. Cerezo; D. Mazurais; J. Zambonino-Infante; J. Gatesoupe; S. Skiba-Cassy; S. Panserat Based on the concept of nutritional programming in mammals, we tested whether an acute hyperglucidic–hypoproteic stimulus during first feeding could induce...

... ). Metabolic programming in the immediate postnatal period . Trends Endocrinol. Metab.   19 , 146 - 152 . Symonds   M. E. , Sebert   S. P. , Hyatt   M. A. , Budge   H. ( 2009 ). Nutritional programming of the metabolic syndrome . Nat. Rev. Endocrinol.   5 , 604 - 610 . Tao   T...