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1-16 of 16
Keywords: NHE
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Journal Articles
Journal:
Journal of Experimental Biology
J Exp Biol (2021) 224 (7): jeb240705.
Published: 15 April 2021
..., compared with the ionic composition of the surrounding seawater. We pharmacologically investigated the role of Na + /H + exchangers (NHE) in intracellular pH regulation and midgut proton and sodium maintenance using the NHE inhibitor 5-( n -ethyl- n -isopropyl)amiloride (EIPA). Basolateral EIPA application...
Journal Articles
Evidence that Rh proteins in the anal papillae of the freshwater mosquito Aedes aegypti are involved in the regulation of acid–base balance in elevated salt and ammonia environments
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Journal:
Journal of Experimental Biology
J Exp Biol (2018) 221 (23): jeb186866.
Published: 26 November 2018
... ( Clark, 2004 ). Acidified water coupled with ion-poor conditions can be particularly challenging, as the excretion of acid–base equivalents is coupled to the uptake of certain ions that are limited ( Vangenechten et al., 1989 ). Ammonium transporter Carbon dioxide Disease vector NHE Rhesus...
Journal Articles
Different mechanisms of Na + uptake and ammonia excretion by the gill and yolk sac epithelium of early life stage rainbow trout
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Journal:
Journal of Experimental Biology
J Exp Biol (2017) 220 (5): 775–786.
Published: 1 March 2017
... + /NH 4 + exchange by the gills, but not the yolk sac skin, of early life stage rainbow trout, possibly resulting from the lack of the key transporter NHE2 in the yolk sac epithelium. Larval fish PNA + ionocyte Na + /H + -exchanger NHE Rhesus glycoproteins Ion regulation...
Journal Articles
Intracellular pH regulation in unstimulated Calliphora salivary glands is Na + dependent and requires V-ATPase activity
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Journal:
Journal of Experimental Biology
J Exp Biol (2012) 215 (8): 1337–1345.
Published: 15 April 2012
... Calliphora vicina salivary gland intracellular pH regulation Na + /H + antiporter NHE vacuolar H + -ATPase V-ATPase intracellular pH insect blowfly BCECF NH 4 Cl prepulse The tubular salivary glands in the blowfly Calliphora vicina consist of a single layer of epithelial cells...
Journal Articles
Comparative characterization of Na + transport in Cyprinodon variegatus variegatus and Cyprinodon variegatus hubbsi : a model species complex for studying teleost invasion of freshwater
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Journal:
Journal of Experimental Biology
J Exp Biol (2012) 215 (7): 1199–1209.
Published: 1 April 2012
... to take up Na + across the apical membrane whereas C. v. variegatus relied on an NHE. Experiments with pharmacological inhibitors were designed to test this hypothesis and identify the most likely transport proteins involved in Na + uptake with the fewest experiments possible (i.e. paired experiments...
Journal Articles
The role of signalling molecules on actin glutathionylation and protein carbonylation induced by cadmium in haemocytes of mussel Mytilus galloprovincialis (Lmk)
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Journal:
Journal of Experimental Biology
J Exp Biol (2009) 212 (22): 3612–3620.
Published: 15 November 2009
...Stefanos Dailianis; Efterpi Patetsini; Martha Kaloyianni SUMMARY This study investigated the role of Na + /H + exchanger(NHE) and signalling molecules, such as cAMP, PKC, PI 3-kinase, and immune defence enzymes, NADPH oxidase and nitric oxide synthase, in the induction of protein glutathionylation...
Journal Articles
NhaA crystal structure: functional–structural insights
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Journal:
Journal of Experimental Biology
J Exp Biol (2009) 212 (11): 1593–1603.
Published: 1 June 2009
... binding and translocation. Based on the crystal structure of NhaA, a model structure of the human Na + /H + exchanger (NHE1) was constructed, paving the way to a rational drug design. * Author for correspondence (e-mail: [email protected] ) 19 11 2008 2009 NhaA NHA NHE Na...
Journal Articles
Branchial expression and localization of SLC9A2 and SLC9A3 sodium/hydrogen exchangers and their possible role in acid–base regulation in freshwater rainbow trout ( Oncorhynchus mykiss )
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Journal:
Journal of Experimental Biology
J Exp Biol (2008) 211 (15): 2467–2477.
Published: 1 August 2008
... on NHE expression were investigated. The elevation of plasma cortisol using intraperitoneal implants caused a significant increase in NHE2 mRNA expression without affecting NHE3 mRNA or protein abundance. Thus, we suggest that NHE2 contributes to acid–base regulation during hypercapnia owing to its...
Journal Articles
Cationic pathway of pH regulation in larvae of Anopheles gambiae
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Journal:
Journal of Experimental Biology
J Exp Biol (2008) 211 (6): 957–968.
Published: 15 March 2008
...; it provides weak HCO 3 – and weaker CO 3 2– anions to the lumen. The cationic pathway consists of H + V-ATPases and Na + /H + antiporters (NHAs), Na + /K + P-ATPases and Na + /H + exchangers (NHEs) along with several(Na + or K + ):amino acid +/– symporters,a.k.a. nutrient amino acid transporters (NATs...
Journal Articles
Intracellular pH homeostasis and serotonin-induced pH changes in Calliphora salivary glands: the contribution of V-ATPase and carbonic anhydrase
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Journal:
Journal of Experimental Biology
J Exp Biol (2008) 211 (5): 805–815.
Published: 1 March 2008
... concanamycin A; (7) concanamycin A removes alkali-going components from multiphasic 5-HT-induced pH changes; (8) NHE activity and a Cl – -dependent process are involved in generating 5-HT-induced pH changes; (9) the salivary glands probably contain a Na + -driven amino acid transporter. We conclude that V...
Journal Articles
Molecular cloning, phylogeny and localization of AgNHA1: the first Na + /H + antiporter (NHA) from a metazoan, Anopheles gambiae
Available to PurchaseMark R. Rheault, Bernard A. Okech, Stephen B. W. Keen, Melissa M. Miller, Ella A. Meleshkevitch, Paul J. Linser, Dmitri Y. Boudko, William R. Harvey
Journal:
Journal of Experimental Biology
J Exp Biol (2007) 210 (21): 3848–3861.
Published: 1 November 2007
... of British Columbia Okanagan, Kelowna, BC, V1V 1V7, Canada 20 8 2007 © The Company of Biologists Limited 2007 2007 sodium potassium exchanger alkalinization AgNHA NHA AgNHE NHE CHA CHE CPA2 African malaria mosquito All organisms regulate their cellular pH, volume...
Journal Articles
Oxygen-sensitive regulatory volume increase and Na transport in red blood cells from the cane toad, Bufo marinus
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Journal:
Journal of Experimental Biology
J Exp Biol (2007) 210 (13): 2290–2299.
Published: 1 July 2007
.... Hyperosmotic shrinkage by a calculated 25% activated a robust Na influx that in the first 30 min had a strong P O 2 dependency with maximal activation at low P O 2 values and a P 50 of ∼5.5 kPa. This activation was completely abolished by the Na/H exchanger (NHE) inhibitor EIPA (10 –4 mol l -1 ). Hyperosmotic...
Journal Articles
A vacuolar-type H + -ATPase and a Na + /H + exchanger contribute to intracellular pH regulation in cockroach salivary ducts
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Journal:
Journal of Experimental Biology
J Exp Biol (2007) 210 (8): 1463–1471.
Published: 15 April 2007
... but contribute both to H + extrusion after an acute dopamine- or NH 4 Cl-induced acid load. vacuolar H + -ATPase V-ATPase NHE BCECF intracellular pH dopamine biogenic amines insect cockroach Periplaneta americana salivary glands References Baumann, O., Dames, P., Kühnel, D. and Walz...
Journal Articles
Regulation of branchial V-H + -ATPase,Na + /K + -ATPase and NHE2 in response to acid and base infusions in the Pacific spiny dogfish ( Squalus acanthias )
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Journal:
Journal of Experimental Biology
J Exp Biol (2005) 208 (2): 345–354.
Published: 15 January 2005
....,Mackenzie, L. and Morrison-Shetlar, A. ( 1999 ). A mechanism for branchial acid excretion in marine fish: identification of multiple Na + /H + antiporter (NHE) isoforms in gills of two seawater teleosts. J. Exp. Biol. 202 , 315 -324. Claiborne, J. B., Edwards, S. L. and Morrison-Shetlar, A. I...
Journal Articles
Characterization of a Basolateral Electroneutral Na + /H + Antiporter in Atlantic Lobster ( Homarus Americanus ) Hepatopancreatic Epithelial Vesicles
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Journal:
Journal of Experimental Biology
J Exp Biol (1996) 199 (3): 643–651.
Published: 1 March 1996
...-potential-sensitive, Na + -accepting ion channel was also demonstrated. The basolateral Na + /H + exchanger physiologically resembles members of the NHE family of Na + /H + antiporters described in vertebrates and departs from the apical electrogenic system previously described in lobster. Whether...
Journal Articles
Role of the Invertebrate Electrogenic 2Na + /1H + Antiporter in Monovalent and Divalent Cation Transport
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Journal:
Journal of Experimental Biology
J Exp Biol (1994) 196 (1): 319–335.
Published: 1 November 1994
... in marine invertebrates . Comp. Biochem. Physiol . 404C , 355 – 372 . Wakabayashi , S. , Sardet , C. , Farfournoux , P. , Counillon , L. , Meloche , S. , Pages , G. and Pouyssegur , J. ( 1992 ). Structure–function of the growth factor-activatable Na/H exchanger (NHE...