... to a cascade of detrimental physiological changes that alter cell operations and ultimately induce death. Nonetheless, some species episodically tolerate near-anoxic environments, and have evolved mechanisms to sustain function even during extended hypoxic periods. While mitochondria are pivotal in central...

... are adapted to these conditions, the mechanisms that sustain mitochondrial integrity and function are not well understood. We determined the rates of respiration and reactive oxygen species (ROS) efflux in the mitochondria of oysters, Crassostrea gigas , acclimated to high (33 psu) or low (15 psu) salinity...

... of anoxic red-eared slider turtle hearts in vivo and in vitro . This was done by measuring the production of H 2 O 2 , the dismutation product of O 2 · − , using the mitochondria-targeted mass-spectrometric probe in vivo MitoB, while in parallel assessing changes in the metabolites driving mitochondrial O 2...

..., post-natal THs, mitochondria and oxidative stress), telomere length and medium-term survival using wild great tits as a model system. While prenatal THs did not significantly affect telomere length a week after hatching (i.e. day 7), they influenced postnatal telomere shortening (i.e. shorter telomeres...

... melanogaster Cyt-c1L Mitochondria Individualization complexes Spermatogenesis References Arama , E. , Agapite , J. and Steller , H. ( 2003 ). Caspase activity and a specific cytochrome C are required for sperm differentiation in Drosophila . Dev. Cell 4 , 687 - 697...

... impairs nutrient absorption. Highlighted Article: Long-term winter food deprivation in sardines elicits energy-saving mechanisms, whereas summer food deprivation has disastrous effects, especially on survival and on use of energy reserves. Bioenergetics Red muscle Mitochondria Respirometry...

... production) of offspring in adulthood, suggesting that elevated maternal CORT may be a signal for early-life adversity and prepare the organism with a predictive, adaptive response to future stressors. Mitochondrial hydrogen peroxide (H 2 O 2 ) production was assessed in isolated mitochondria using...

... in liver, oxidative muscle and hearts of most stickleback. Similarly, in mammalian brain mitochondria, complex II activity declines to a greater extent than complex I with a decrease in temperature from 37°C to 28°C ( Pamenter et al., 2018 ). The increase in succinate-fueled respiration in response...

... individual fitness, group function and species communities in different environments. Locomotion Metabolic rate Muscle Mitochondria Temperature Exercise Allocation trade-off Australian Research Council http://dx.doi.org/10.13039/501100000923 DP220101342 Limited resources...

... in mitochondrial metabolism between thermal acclimation states in birds. Some functions of the mitochondria covary with thermogenic capacity and basal maintenance costs in patterns that are dependent on temperature and body mass. We are grateful to the Corporation de la Forêt d'Enseignement et de Recherche...

... ) and, therefore, they may be poorly correlated or uncorrelated with SMR. Nevertheless, we found individual variation in SMR by F. grandis was positively correlated with TFL and with maximum uncoupled electron transport system respiration by myocardial mitochondria (ETS NS ) ( Table 3 ). Notably...

...James Robertson; Andrew Jeffs; Christopher Hedges; Anthony J. R. Hickey ABSTRACT The anaesthetic isoeugenol has been used as metabolic suppressant for commercial transport of live lobsters in order to decrease energy expenditure and improve survival. Given the central role of mitochondria...

..., indicating that short-term thermal transients are an important aspect of habitat quality for zebrafish. Mitochondria Temperature Reactive oxygen species Catalase Oxidative damage Respiratory control ratio Australian Research Council http://dx.doi.org/10.13039/501100000923 DP190101168...

..., mitochondria and hypoxia-inducible factors, as well as convergent pathways involved in energy regulation, development, reproductive investment and energy storage. The details of these mechanisms are only known from a few model systems, and more comparative studies are needed. We make two main recommendations...

... minutes of anoxia or OGD and exhibit large-scale deleterious Ca 2+ influx during hypoxia ( Nathaniel et al., 2009 ; Peterson et al., 2012b ). Furthermore, at the organelle level and relative to mice, NMR brain mitochondria better retain respiration capacity, have lower H 2 O 2 emission rates and stable...

... availability during hypoxia–reoxygenation (H/R). We investigated the effects of acute H/R stress (15 min at ∼0% O 2 and 10 min reoxygenation) on isolated mitochondria from the gill and the digestive gland of C. gigas respiring on different substrates (pyruvate, glutamate, succinate, palmitate...

... for its hypoxia tolerance associated with metabolic rate depression, yet the mechanisms that sustain mitochondrial function during oxygen fluctuations are not well understood. We used top-down metabolic control analysis (MCA) to determine aerobic capacity and control over oxygen flux in the mitochondria...

... confirmed the involvement of K ATP in mitochondria with TMRE imaging, as hypoxia rapidly (<5 min) depolarized mitochondria in a mK ATP channel-sensitive manner. We conclude that mK ATP channels initiate a neuroprotective pathway in goldfish HCs to maintain [Ca 2+ ] i and avoid excitotoxicity in hypoxia...

... , A. , Guedouari-Bounihi , H. , Lenoir , V. , Andriamihaja , M. , Blachier , F. and Bouillaud , F. ( 2015 ). Oxidation of H 2 S in mammalian cells and mitochondria . Methods Enzymol. 554 , 201 - 228 . 10.1016/bs.mie.2014.11.042 Ahn , B.-H. , Kim , H.-S. , Song , S...

..., indicating the important role of acclimation in their capacity to adjust to thermal challenges. Climate change Mitochondria Reactive oxygen species Aquatic ectotherms Thermal sensitivity Metabolism Groupe de Recherche Interuniversitaire en Limnologie Natural Sciences...