... and after submaximal running. In addition, we determined the activity of PDHt and the abundance of PDK and PDH phosphatase (PDP)1 as possible explanations for any variation in PDHa. Unlike hierarchical regulation, changes in muscle metabolic regulation in response to hypoxia acclimation are poorly...

... in enzyme level, and ‘metabolic regulation’, involving the modulation of the activity of preexisting enzyme, regulate flux. We outline these approaches and provide examples to show their applicability to problems of interest to comparative physiologists. * Author for correspondence ( suarez...

.... Physiol. 276 , H50 -H57. * Author for correspondence (e-mail: [email protected] ) 18 1 2005 © The Company of Biologists Limited 2005 2005 metabolic regulation respiration mitochondria BMR V̇ O 2max allometry Metabolic rates scale allometrically...

... sensitivity of the proton leakage rate to changes of membrane potential will confer better flexibility for metabolic regulation(mild uncoupling) in response to temperature change. These seasonal alterations in mitochondrial functions suggest modifications of energy metabolism in eurythermal and euryoxic...

...P. W. Hochachka SUMMARY Two views currently dominate experimental approaches to metabolic regulation. The first, let us call it Model 1, assumes that cells behave like a watery bag of enzymes. The alternative Model 2, however, assumes that 3-dimensional order and structure constrain metabolite...