... between the activation kinetics or voltage-dependence of Na + and K + currents. Conductance levels, however, did vary. Maximum Na + conductance ( g Na) in S. sepiodea was significantly less than in the Loligo species. K + conductance ( g K) was highest in L. pealei , intermediate in L. plei and smallest...

... at altered external [K + ] and by replacing internal K + with Cs + , we determined that the outward currents were carried by K + . The outward currents consist of a transient A-type K + current (K A ) and a delayed-rectifier-like K + current (K D ). Amongst the cells studied, we observed two distinct groups...

... and do not reach the usual amplitudes of 15–20 mV but only of 6–10 mV. In addition, the amplitudes of K + currents are increased at depolarizations of more than 20 mV by at least 30 %. Hyperpolarization- and depolarization-activated Na + current amplitudes are increased, whereas the Ca 2+ current...

... . These three toxins (KTX, ChTX and DTX) did not block K + currents recorded from nerve fibres in P. clarkii . The pharmacology of the K + channels in these two arthropods did not conform to that previously described for K + channels in other species. Current-clamp experiments clearly indicated that the venom...

...-aminopyridine (4-AP)-sensitive K + current and a 4-AP-insensitive K + current. We have found that a subset of LFS neurons exhibits an exclusively excitatory, biphasic response to FMRFamide, consisting of a transient depolarization followed by a prolonged depolarization of reduced magnitude. Over a period of 29...

...Mary T. Lucero; Nansheng Chen ABSTRACT We performed whole-cell voltage-clamp experiments on isolated olfactory receptor neurons from the squid Lolliguncula brevis . Total outward currents were composed of three identifiable K + currents: a delayed rectifier K + current that showed slow inactivation...

... experiments, D-glucose evoked a small current with a reversal potential close to that of voltage-dependent K + currents. We conclude that D-glucose activates a K + current in CHH-immunoreactive cells that, in normal saline, induces a hyperpolarization. We propose that this enables glucose to regulate directly...