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Keywords: Hypoxic ventilatory response
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Journal Articles
J Exp Biol (2023) 226 (19): jeb246185.
Published: 6 October 2023
...Maiah E. M. Devereaux; Sarah Chiasson; Kate F. Brennan; Matthew E. Pamenter ABSTRACT Damaraland mole-rats ( Fukomys damarensis ) are a hypoxia-tolerant fossorial species that exhibit a robust hypoxic metabolic response (HMR) and blunted hypoxic ventilatory response (HVR). Whereas the HVR of most...
Journal Articles
J Exp Biol (2023) 226 (19): jeb246186.
Published: 6 October 2023
...Maiah E. M. Devereaux; Matthew E. Pamenter ABSTRACT Fossorial Damaraland mole-rats ( Fukomys damarensis ) mount a robust hypoxic metabolic response (HMR) but a blunted hypoxic ventilatory response (HVR) to acute hypoxia. Although these reflex physiological responses have been described previously...
Journal Articles
J Exp Biol (2023) 226 (6): jeb245324.
Published: 29 March 2023
...: The metabolic and thermoregulatory responses of Malagasy tenrecs to acute hypoxia and hypercapnia approaches that of ectothermic reptiles. Hypercapnia Hypoxic ventilatory response Hypoxic metabolic response Thermogenesis Metabolic rate depression Natural Sciences and Engineering Research...
Journal Articles
J Exp Biol (2022) 225 (4): jeb196725.
Published: 21 February 2022
... hypoxic ventilatory response, robust metabolic rate suppression and decreased thermogenesis ( Mortola, 1999 ; Mortola et al., 1989 ). In most adult hypoxia-intolerant mammals, ventilatory and metabolic responses to hypoxia are regulated by excitatory glutamatergic signalling pathways ( Pamenter et al...
Journal Articles
J Exp Biol (2021) 224 (19): jeb242972.
Published: 14 October 2021
... that, like many other semi-aquatic and fossorial small mammals, star-nosed moles would exhibit: (i) a blunted (i.e. delayed or reduced) hypoxic ventilatory response, (ii) a reduced metabolic rate and (iii) a lowered body temperature ( T b ) in hypoxia. We thus non-invasively measured these variables from...
Includes: Supplementary data
Journal Articles
J Exp Biol (2021) 224 (18): jeb231936.
Published: 17 September 2021
... of either paralog of Hif-1α greatly reduces hypoxia tolerance, indicating the importance of both paralogs to the hypoxic response. Here, with an emphasis on the cardiorespiratory system, we focus on the role of Hif-1α in the hypoxic ventilatory response and the regulation of cardiac function. We explore...
Journal Articles
Journal Articles
Journal Articles
J Exp Biol (2020) 223 (5): jeb219360.
Published: 11 March 2020
... volumes), for mice that were caught and tested at their native altitudes and those lab-raised in normoxia. Lab-raised progeny of each population were also tested at post-natal day (P)7, 14, 21 and 30. Highlanders developed an enhanced hypoxic ventilatory response by P21, concurrent with the full...
Includes: Supplementary data
Journal Articles
J Exp Biol (2019) 222 (7): jeb198622.
Published: 1 April 2019
... that independently colonized the high Andes. We compared ducks from high-altitude populations in Peru (Lake Titicaca at ∼3800 m above sea level; Chancay River at ∼3000–4100 m) with closely related populations or species from low altitude. Hypoxic ventilatory responses were measured shortly after capture...
Journal Articles
J Exp Biol (2019) 222 (3): jeb191197.
Published: 7 February 2019
.... Published by The Company of Biologists Ltd 2019 http://www.biologists.com/user-licence-1-1/ Summary: Naked mole rats enter into a coma-like state upon reoxygenation following severe hypoxia but do not pay off an oxygen debt. Hypoxic metabolic response Hypoxic ventilatory response...
Journal Articles