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Keywords: Genome
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Journal Articles
J Exp Biol (2020) 223 (Suppl_1): jeb218198.
Published: 1 February 2020
... technological innovations like next-generation sequencing and CRISPR-Cas9 genome editing, the time is ripe to move beyond the big 6. In this review, we chart a 10-step path to this goal, using our own experience with the Aedes aegypti mosquito, which we built into a model organism for neurobiology in one decade...
Journal Articles
J Exp Biol (2015) 218 (4): 598–611.
Published: 15 February 2015
... a common bilaterian/cnidarian ancestor without the bona fide central nervous system. Ctenophores, or comb jellies, represent an example of extensive parallel evolution in neural systems. First, recent genome analyses place ctenophores as a sister group to other animals. Second, ctenophores have a smaller...
Journal Articles
J Exp Biol (2012) 215 (15): 2535–2544.
Published: 1 August 2012
... focused on understanding its neurochemistry at any level. Recently, D. pulex has been the subject of extensive genome and transcriptome sequencing, and it is currently the only crustacean with a fully sequenced, publicly accessible genome. Although the molecular work was initiated for gene-based...
Journal Articles
J Exp Biol (2010) 213 (6): 912–920.
Published: 15 March 2010
... their thermal tolerances. Reductionist studies at the molecular level can contribute to this analysis by revealing how much change in sequence is needed to adapt proteins to warmer temperatures — thus providing insights into potential rates of adaptive evolution — and determining how the contents of genomes...
Journal Articles
J Exp Biol (2005) 208 (22): 4273–4282.
Published: 15 November 2005
.... An alternative strategy for identification of echinoid SALMFamides was provided by sequencing the genome of the sea urchin Strongylocentrotus purpuratus . Analysis of whole-genome shotgun sequence data using the Basic Local Alignment Search Tool (BLAST) identified a contig (347664) that contains a coding region...