...Xuan Huang; Adriano Senatore; Taylor F. Dawson; Quyen Quan; John David Spafford SUMMARY Voltage-gated calcium channels in the Ca v 2 channel class are regulators of synaptic transmission and are highly modified by transmitter inputs that activate synaptic G-protein-coupled receptors (GPCRs...

...Katarzyna Sobierajska; Hanna Fabczak; Stanislaw Fabczak SUMMARY Immunological techniques and high-resolution FRET analysis were employed to investigate the in vivo colocalization and interaction of phosducin(Pdc) with the βγ-subunits of G-protein (Gβγ) in the ciliate Blepharisma japonicum...

...Yasuo Nakaoka; Tohru Tanaka; Toshihiko Kuriu; Tomohisa Murata ABSTRACT The possible involvement of G-proteins in cold-sensory transduction was examined using voltage-clamped Paramecium multimicronucleatum into which non-hydrolyzable guanosine nucleotide analogues had been applied intracellularly...

... by a variety of interactive second messenger systems, which provide necessary tuning for an appropriate control of intracellular calcium level. If this signal transduction pathway included a G-protein it should be possible to mimic receptor-mediated responses by introducing GTP-γ-S into the cell. Conse...