... secretion can be regulated by circulating levels of estradiol. However, the effect of estradiol on CRH neuron excitability is less clear. Here, we show that chronic estradiol replacement following ovariectomy increases two types of potassium channel currents in CRH neurons: fast inactivating voltage-gated...

... resources alter neural systems to stimulate mating behavior. Compared with other females, females that were housed with and explored nest boxes had higher estradiol, higher preproenkephalin (PENK) mRNA and lower levels of D1 and D2 dopamine receptor mRNA in the medial preoptic area (mPOA); a region in which...

... directly to low glucose availability by increasing progesterone production; this may contribute to homeostatic processes that positively regulate blood glucose. 2-DG Bromopyruvic acid Glucose homeostasis Steroidogenesis Estradiol Reproduction is carefully regulated in most species...

... investigated the effect of total ovariectomy, prepubertal ovariectomy, unilateral ovariectomy, and total ovariectomy followed by exogenous estradiol, dihydrotestosterone or testosterone treatment, on female growth in comparison to males and reproductively active females. The present results and the results...

... the presence of intersexual variation in sex steroid hormone profiles, as estradiol concentrations of female snakes increased significantly prior to spring mating activity. Importantly, the percentage change in body mass did not differ significantly between snakes in the hibernation treatments,indicating...

...Maureen J. Devlin; Daniel E. Lieberman SUMMARY Although mechanical loading can stimulate cortical bone growth, little is known about how individual physiology affects this response. This study demonstrates that in vivo variation in estradiol (E 2 )level alters osteoblast sensitivity to exercise...

..., we have examined the influence of the female sex hormone 17 β-estradiol (E 2 ). E 2 was not sufficient to elicit an increase in hepatic zinc concentrations or MT mRNA levels. E 2 administration did, however, result in increased levels of MT in the nuclear fraction as well as overall hepatic MT...