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Keywords: Epigenetics
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Journal Articles
J Exp Biol (2021) 224 (Suppl_1): jeb239319.
Published: 24 February 2021
... of these mechanisms and continuum, I also present how the interplay of the microbiome, epigenetics and parental effects creates additional avenues for rapid acclimatization. To consider under what conditions epigenetic inheritance has a more substantial role, I propose investigation into the offset of timing...
Journal Articles
J Exp Biol (2020) 223 (23): jeb214999.
Published: 07 December 2020
... Epigenetics Aquaculture Nutritional programming Environmental factors such as nutritional interventions during early developmental stages exert long-lasting metabolic and physiological changes in mammals ( Burdge and Lillycrop, 2010 ) and other vertebrates, including fish ( Izquierdo et al., 2015...
Includes: Supplementary data
Journal Articles
J Exp Biol (2020) 223 (13): jeb220632.
Published: 03 July 2020
...Cheryl Walker; Warren Burggren ABSTRACT The epigenome determines heritable patterns of gene expression in the absence of changes in DNA sequence. The result is programming of different cellular-, tissue- and organ-specific phenotypes from a single organismic genome. Epigenetic marks that comprise...
Journal Articles
J Exp Biol (2020) 223 (3): jeb217422.
Published: 31 January 2020
...Ila Mishra; Aakansha Sharma; Abhilash Prabhat; Twinkle Batra; Indu Malik; Vinod Kumar ABSTRACT We hypothesised that daily food availability times serve as an ‘epigenetic’ factor and affect reproductive physiology in continuously reproducing species. This we tested by measuring mRNA expression...
Journal Articles
J Exp Biol (2019) 222 (17): jeb208918.
Published: 05 September 2019
...Naim M. Bautista; Warren W. Burggren ABSTRACT Genomic modifications occur slowly across generations, whereas short-term epigenetic inheritance of adaptive phenotypes may be immediately beneficial to large numbers of individuals, acting as a bridge for survival when adverse environments occur...
Includes: Supplementary data
Journal Articles
J Exp Biol (2019) 222 (15): jeb203620.
Published: 05 August 2019
... by histone modifications such as histone acetylation. Here, we investigated a group of key epigenetic modifiers, histone deacetylases (HDAC), which are known to play an important role in many biological processes such as development, healing and regeneration. Through our transcriptome data, we identified...
Includes: Supplementary data
Journal Articles
In collection:
Neuroethology
J Exp Biol (2019) 222 (2): jeb188649.
Published: 16 January 2019
... Epigenetics Nicrophorus vespilloides Social behaviour Social neuroscience Summary: Behavioural state has more influence on gene expression than social context or individual flexibility during a transition to parental care, whereas cytosine methylation is not associated with differential gene...
Includes: Supplementary data
Journal Articles
J Exp Biol (2018) 221 (23): jeb153163.
Published: 26 November 2018
... of acceptance of genetic accommodation in some cases is related to a lack of information on its molecular mechanisms. However, recent reports of epigenetic transgenerational inheritance now provide a plausible mechanism through which genetic accommodation may act, and we review this research here. We also...
Journal Articles
J Exp Biol (2017) 220 (23): 4330–4338.
Published: 01 December 2017
... and subsequent generations protection from future starvation events. Bioenergetics Diet Epigenetics Fasting Nutrition Weight loss Limitation in the availability of food is an omnipresent challenge faced by many animal populations. The durations of these events can be brief, and cause...
Journal Articles
J Exp Biol (2017) 220 (20): 3686–3694.
Published: 15 October 2017
... affected plasma metabolites or global epigenetic modifications in juvenile fish after the challenge test. In conclusion, our results demonstrated that an acute hypoxic stimulus during early development alone or combined with a hyperglucidic stimulus at first feeding can modify growth performance...
Includes: Supplementary data
Journal Articles
J Exp Biol (2017) 220 (19): 3579–3587.
Published: 01 October 2017
...-related hormones. A big challenge, however, is in determining the history of exposure of an organism to stress, because the release of stress hormones can show an acute (and recent) but not a sustained exposure to stress. Epigenetic tools provide an alternative option to evaluate past exposure to long...
Includes: Supplementary data
Journal Articles
J Exp Biol (2015) 218 (15): 2365–2372.
Published: 01 August 2015
... consideration of rapid-response acclimatization mechanisms. These rapid mechanisms such as parental effects that can contribute to trans-generational acclimatization (e.g. epigenetics) have, however, been identified as important contributors to offspring response in other systems. We present the first evidence...
Includes: Supplementary data
Journal Articles
J Exp Biol (2015) 218 (11): 1787–1795.
Published: 01 June 2015
... and biochemical changes; however, much remains to be discovered about the molecular mechanisms involved. Given the seasonal nature of hibernation, it stands to reason that underlying plastic epigenetic mechanisms should exist. One such form of epigenomic regulation involves the reversible modification of cytosine...
Journal Articles
J Exp Biol (2015) 218 (1): 32–40.
Published: 01 January 2015
...Per Jensen; Hans H. Hoppeler In this review, it is argued that greatly improved understanding of domestication may be gained from extending the field of behaviour genetics to also include epigenetics. Domestication offers an interesting framework of rapid evolutionary changes caused by well-defined...
Journal Articles
J Exp Biol (2015) 218 (1): 7–13.
Published: 01 January 2015
...Denis Noble; Hans H. Hoppeler Experimental results in epigenetics and related fields of biological research show that the Modern Synthesis (neo-Darwinist) theory of evolution requires either extension or replacement. This article examines the conceptual framework of neo-Darwinism, including...
Includes: Supplementary data
Journal Articles
J Exp Biol (2015) 218 (1): 21–31.
Published: 01 January 2015
... 50% of patients. Although a genetic component accounts for some cases of MDD, it is now clearly established that MDD results from strong gene and environment interactions. Such interactions could be mediated by epigenetic mechanisms, defined as chromatin and DNA modifications that alter gene...
Journal Articles
J Exp Biol (2015) 218 (1): 107–113.
Published: 01 January 2015
... ( dustin.marshall@monash.edu ) Competing interests The author declares no competing financial interests. © 2015. Published by The Company of Biologists Ltd 2015 Epigenetics Paternal effects Sperm Classic quantitative genetics theory assumes that sperm are vehicles for genes and nothing...
Journal Articles
J Exp Biol (2015) 218 (1): 59–70.
Published: 01 January 2015
...Michael Daniel; Trygve O. Tollefsbol; Hans H. Hoppeler Epigenetic mechanisms play a pivotal role in the expression of genes and can be influenced by both the quality and quantity of diet. Dietary compounds such as sulforaphane (SFN) found in cruciferous vegetables and epigallocatechin-3-gallate...
Journal Articles
J Exp Biol (2015) 218 (1): 80–87.
Published: 01 January 2015
...Warren W. Burggren; Hans H. Hoppeler Epigenetic studies of both intragenerational and transgenerational epigenetic phenotypic modifications have proliferated in the last few decades. However, the strong reductionist focus on mechanism that prevails in many epigenetic studies to date has diverted...
Journal Articles
J Exp Biol (2015) 218 (1): 114–122.
Published: 01 January 2015
...Roberto Bonasio; Hans H. Hoppeler Epigenetics studies the emergence of different phenotypes from a single genotype. Although these processes are essential to cellular differentiation and transcriptional memory, they are also widely used in all branches of the tree of life by organisms that require...