... at each step when the substrates pyruvate, malate, glutamate and succinate were sequentially added to stimulate electron transport chain components, and responded in an expected manner to the known mitochondrial complex inhibitors oligomycin and antimycin A (Fig. 2 A). The addition of cytochrome c led...

... in ducklings fasted for 6 days generates a lower membrane potential, which triggers a decreased proton leak activity and thus a higher coupling efficiency. We propose that the main site of action would be located at the level of co-enzyme Q pool/complex III of the electron transport chain. * Author...

... anoxia at 5°C and during simulated acute anoxia/reoxygenation. Mitochondrial respiration, electron transport chain activities, enzyme activities, proton conductance and membrane potential were measured in permeabilised cardiac fibres and isolated mitochondria. Two weeks of anoxia exposure at 5°C resulted...

... electron transport chain at four separate sites that converge in the reduction of coenzyme Q (Efremov et al., 2010). Metabolism of different substrates results in electron donation to specific complexes or sites (Efremov et al., 2010). Oxidation of glutamate, malate and pyruvate provides NADH for electron...

... tissues in mice and humans. Recent work has begun to analyze the similarities and differences in transcriptional changes in aging among different species. Most age-related expression changes are specific for a given species, but genes in one pathway(the electron transport chain pathway) show common age...

... respiration rates obtained from frogs submerged in hypoxic water for 4 months were half those of control animals. This 50 % reduction in respiration rate in hypoxic hibernation was due to a reduction in electron transport chain activity and consequent decrease in mitochondrial membrane potential. We conclude...