... , an eicosanoid inflammatory mediator. RNA interference (RNAi) using double-stranded RNAs specific to SePGDH or SePGR suppressed their expression levels. The RNAi treatment resulted in an excessive and fatal melanization of larvae even after a non-pathogenic bacterial infection. Phenoloxidase (PO) activity...

.... LTB 5 was equally effective as LTB 4 at displacing [ 3 H]LTB 4 , while other eicosanoids tested were without significant effect. It is suggested that the putative receptors for LTB 4 on trout macrophages are similar to the high-affinity receptors for this compound reported to occur on mammalian...