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Keywords: Drosophila
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Journal Articles
J Exp Biol jeb.243708.
Published: 28 April 2022
... respond to temperature is still unclear. Here, we describe an automated tracking method for studying the thermotactic behaviors of Drosophila larvae and adults. We build optimal experimental setups to capture behavioral recordings and analyze them using free software, Fiji and TrackMate, which do...
Journal Articles
J Exp Biol (2021) 224 (21): jeb242698.
Published: 4 November 2021
... to a better understanding of treatment options; however, there is no single cause of atrophy identified to date. To gain insight into this problem, we chose to investigate changes in protein profiles during muscle atrophy in Manduca sexta and Drosophila melanogaster . The use of insect models provides...
Includes: Supplementary data
Journal Articles
J Exp Biol (2021) 224 (21): jeb242740.
Published: 25 October 2021
...Louis K. Scheffer; Ian A. Meinertzhagen ABSTRACT Understanding the structure and operation of any nervous system has been a subject of research for well over a century. A near-term opportunity in this quest is to understand the brain of a model species, the fruit fly Drosophila melanogaster...
Journal Articles
J Exp Biol (2021) 224 (18): jeb240432.
Published: 1 October 2021
... diet to study the pathophysiology of diet-induced metabolic disease in Drosophila melanogaster . High-sugar diets produce hyperglycemia, obesity, insulin resistance and cardiomyopathy in flies, along with ectopic accumulation of toxic lipids, or lipotoxicity. Stearoyl-CoA desaturase 1 is an enzyme...
Includes: Supplementary data
Journal Articles
J Exp Biol (2021) 224 (16): jeb242267.
Published: 20 August 2021
...Floris van Breugel ABSTRACT Nearly all motile organisms must search for food, often requiring multiple phases of exploration across heterogeneous environments. The fruit fly, Drosophila , has emerged as an effective model system for studying this behavior; however, little is known about the extent...
Includes: Supplementary data
Journal Articles
In collection:
Neuroethology
J Exp Biol (2021) 224 (14): jeb242219.
Published: 23 July 2021
... Bender , J. A. and Dickinson , M. H. ( 2006 ). A comparison of visual and haltere-mediated feedback in the control of body saccades in Drosophila melanogaster . J. Exp. Biol. 209 , 4597 - 4606 . 10.1242/jeb.02583 Borst , A. , Haag , J. and Mauss , A. S. ( 2020...
Includes: Supplementary data
Journal Articles
J Exp Biol (2021) 224 (9): jeb240986.
Published: 6 May 2021
...Yan Wang; Sirisha Burra; Michael J. Galko ABSTRACT Holometabolous insects undergo a complete transformation of the body plan from the larval to the adult stage. In Drosophila , this transformation includes replacement of larval epidermal cells (LECs) by adult epidermal cells (AECs). AECs...
Includes: Supplementary data
Journal Articles
J Exp Biol (2021) 224 (6): jeb238006.
Published: 25 March 2021
... of the species Drosophila melanogaster exhibit aggression in same-sex pairings, but the strategies used are sexually dimorphic. We have begun to explore the biological basis for the differing aggression strategies, and the cues promoting one form of aggression over the other. Here, we describe a line...
Includes: Supplementary data
Journal Articles
J Exp Biol (2021) 224 (1): jeb232116.
Published: 7 January 2021
... system and several behavioural aspects in insects. In particular, tyramine (TA) and octopamine (OA) and their associated receptors orchestrate physiological processes such as feeding, locomotion and metabolism. Here, we show that monoterpenes not only act as biopesticides in Drosophila species but also...
Includes: Supplementary data
Journal Articles
J Exp Biol (2020) 223 (22): jeb223867.
Published: 20 November 2020
... as a RONS scavenger, influences the regulation of genetic elements in endogenous antioxidant pathways. To investigate the role of curcumin in sex-specific in vivo responses to oxidative stress, Drosophila were reared on media supplemented with 0.25, 2.5 or 25 mmol l −1 curcuminoids (consisting of curcumin...
Includes: Supplementary data
Journal Articles
J Exp Biol (2020) 223 (21): jeb219592.
Published: 2 November 2020
...Dina Malkeyeva; Elena Kiseleva; Svetlana Fedorova ABSTRACT Hsp67Bc in Drosophila melanogaster is a member of the small heat shock protein family, the main function of which is to prevent the aggregation of misfolded or damaged proteins. Hsp67Bc interacts with Starvin and Hsp23, which are known...
Journal Articles
J Exp Biol (2020) 223 (14): jeb228379.
Published: 22 July 2020
... because such diets reduce glycogen stores and thereby energy expenditure via physical activity. To explore the effect of a low-carbohydrate diet on activity and glycogen utilisation, we fed adult Drosophila melanogaster a standard or low-carbohydrate diet for 9 days and measured patterns of flight...
Includes: Supplementary data
Journal Articles
J Exp Biol (2020) 223 (8): jeb220608.
Published: 23 April 2020
... a great resource for developing new materials, insect adhesives have been little studied so far. Here, we examined the adhesive properties of the larval glue of Drosophila melanogaster . This glue is made of glycosylated proteins and allows the animal to adhere to a substrate during metamorphosis. We...
Includes: Supplementary data
Journal Articles
J Exp Biol (2020) 223 (Suppl_1): jeb208215.
Published: 1 February 2020
... fate determination, and the extraordinary diversity of behavioral responses to chemical cues. References Alkhori , L. , Öst , A. and Alenius , M. ( 2014 ). The corepressor Atrophin specifies odorant receptor expression in Drosophila . FASEB J. 28 , 1355 - 1364 . 10.1096/fj.13...
Journal Articles
J Exp Biol (2019) 222 (3): jeb191049.
Published: 8 February 2019
... becomes unavailable. Starvation resistance is strongly influenced by ecological and evolutionary history, yet the genetic basis for the evolution of starvation resistance remains poorly understood. The fruit fly Drosophila melanogaster provides a powerful model for leveraging experimental evolution...
Includes: Supplementary data
Journal Articles
J Exp Biol (2018) 221 (24): jeb191429.
Published: 14 December 2018
... species is not known. We therefore sought to investigate whether sleep is important for optimizing attention in an invertebrate species, the genetic model Drosophila melanogaster . We developed a high-throughput paradigm to measure visual attention in freely walking Drosophila , using competing foreground...
Includes: Supplementary data
Journal Articles
J Exp Biol (2018) 221 (11): jeb159533.
Published: 12 June 2018
.... , Teder-Laving , M. , Azevedo , R. V. D. M. , Hayward , C. , van Mill , J. , Vogelzangs , N. , Green , E. W. , et al. ( 2013 ). A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila . Mol. Psychiatry   18 , 122 - 132...
Journal Articles
J Exp Biol (2017) 220 (23): 4492–4501.
Published: 1 December 2017
... cope with sudden changes in the environment. Here, we sought to modify the maternal mRNA contribution to offspring embryos and test for maternal effects on acute thermal tolerance in early embryos of Drosophila melanogaster . We drove in vivo overexpression of a small heat shock protein gene ( Hsp23...
Journal Articles
In collection:
Neuroethology
J Exp Biol (2017) 220 (12): 2218–2227.
Published: 15 June 2017
... been deposited in the Dryad Digital Repository ( Mureli et al., 2017 ): http://dx.doi.org/10.5061/dryad.v6q20 . References Bartussek , J. and Lehmann , F.-O. ( 2016 ). Proprioceptive feedback determines visuomotor gain in Drosophila . R. Soc. Open Sci.   3 , 150562 . 10.1098...
Includes: Supplementary data
Journal Articles
In collection:
Neuroethology
J Exp Biol (2017) 220 (10): 1812–1819.
Published: 15 May 2017
...Tom Retzke; Michael Thoma; Bill S. Hansson; Markus Knaden ABSTRACT The genetic toolbox in Drosophila melanogaster offers a multitude of different effector constructs to silence neurons and neuron populations. In this study, we investigated the potencies of several effector genes – when expressed...
Includes: Supplementary data