...-dihydropyridine receptor DHPR Ca V 1.1 α 1 S L-type Excitation–contraction coupling Skeletal muscle Eight years ago, I summarized the depth of knowledge concerning the basic mechanism of excitation–contraction (EC) coupling in skeletal muscle in an article entitled ‘Bridging the myoplasmic gap...

...+ release, respectively, the density of dihydropyridine receptors (DHPRs) and ryanodine receptors (RyRs) was examined,using high-affinity (–)-enantiomers of dihydropyridine and ryanodine labelled with fluorophores. To investigate Ca 2+ utilization in the skin, the systemic and local activity of the enzyme...