... models: Hill-type and cross-bridge. We found that no combination of these processes can self-consistently reproduce classic data such as twitch and tetanus. Rather, additional dynamics are needed following calcium activation and facilitating cross-bridge cycling, such as for cooperative myofilament...

... enhancement (rFE), remain unknown. When myofibrils are actively stretched while cross-bridge cycling is inhibited, rFE is substantially reduced, suggesting that cross-bridge cycling is essential to produce rFE. Our purpose was to further investigate the role of cross-bridge cycling in rFE by investigating...

... this result. During cross-bridge cycling, ATP is used to power the attachment–detachment cycles and simultaneously produce force. How can the decrease in the number of cycling cross-bridges explain the reduction in force along with the decrease in ATP consumption? The amount of force developed by a muscle can...