...Rachel L. Sutcliffe; Shaorong Li; Matthew J. H. Gilbert; Patricia M. Schulte; Kristi M. Miller; Anthony P. Farrell ABSTRACT We examined cardiac pacemaker rate resetting in rainbow trout following a reciprocal temperature transfer. In the original experiment, performed in winter, 4°C-acclimated fish...

... and mitochondrial investments of the heart, indicating economy of design at the cellular level of the oxygen cascade in an aerobic organ. Capillarity Cardiac Mammal Mitochondria Myofibrils Predation The size of the heart is determined by the magnitude of the volume loads and the pressure loads...

... beats min −1 , 0.705±0.048 ml O 2 g −1 h −1 ) at an ambient temperature ( T a ) of 31°C. f H had an inverse linear relationship with T a to a maximum of 630±19 beats min −1 at a T a of 20°C. During entry into torpor at a T a of 20°C, f H slowed primarily as a result of episodic periods of cardiac...

... of mutations in these isoforms illustrate how myosin is adapted for specific functions. Muscle Contraction Human Cardiac Skeletal Myosins are a large family of ATP-driven mechanoenzymes that generate a wide range of mechanical activities using the actin cytoskeleton as a track to move along...

... for correspondence (e-mail: [email protected] ) 19 12 2006 © The Company of Biologists Limited 2007 2007 physiome mathematical modelling cardiac multi-scale Coupling genomic data to physiological function is the aim of biology in the post-genomic era. Quantitative descriptions...

...George A. Ordway; Daniel J. Garry SUMMARY Myoglobin is a cytoplasmic hemoprotein, expressed solely in cardiac myocytes and oxidative skeletal muscle fibers, that reversibly binds O 2 by its heme residue, a porphyrin ring:iron ion complex. Since the initial discovery of its structure over 40 years...

...-Arg-Asn-Phe-Leu-Arg-Phe-NH 2 ) and DF 2 (Asp-Arg-Asn-Phe-Leu-Arg-Phe-NH 2 ), increased the rate and amplitude of spontaneous cardiac contractions and increased the amplitude of excitatory junctional potentials (EJPs) in the deep extensors. Both effects were dose-dependent, but threshold and EC50...

...-exposure), and (ii) to evaluate the potential mechanisms of catecholamine release from the major sites of storage, the systemic heart and posterior cardinal vein (PCV). Adrenaline and noradrenaline were stored at roughly equivalent concentrations (approximately 20 μ gg - 1 ) in cardiac tissue, whereas...