... tolerance, and CT max correlates well with current species distributions of insects, including Drosophila . Here, we examined the function of the central nervous system (CNS) in five species of Drosophila with different heat tolerances, while they were exposed to either constant high temperature...

... acclimation. Our results demonstrate that CT min and CCO correlate strongly with a spreading depolarization (SD) within the central nervous system (CNS). We show that this SD is associated with a rapid increase in extracellular [K + ] within the CNS causing neuronal depolarization that silences the CNS...

... into the intracellular compartment), and (2) the final and catastrophic outcome from acute mechanical damage to the CNS is due to processes that are extraordinarily complex and will likely require several `therapies' acting in concert to produce interventions that are clinically useful. Here we show that application...

... preparation, appear to originate within, or in the vicinity of, the anterior ganglion and which impose an anterior polarity on the initial cellular responses to selective glial disruption. They could be uncommitted progenitor cells, such as have been (hown to exist in the vertebrate CNS ( Raff, Miller...