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Journal: Journal of Experimental Biology
J Exp Biol (2005) 208 (6): 1045–1052.
Published: 15 March 2005
... ) receptor (IP 3 R) and subsequent release of Ca 2+ from the sarcoplasmic reticulum (SR). IP 3 R-mediated release of SR Ca 2+ causes calcium-induced calcium release (CICR) via the ryanodine receptor (RyR), which can be sensitized by cyclic adeninediphosphate ribose (cADPR). cADPR is synthesized from NAD...