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Keywords: Allostery
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Journal Articles

Allosteric mechanisms underlying the adaptive increase in hemoglobin–oxygen affinity of the bar-headed goose

Agnieszka Jendroszek, Hans Malte, Cathrine B. Overgaard, Kristian Beedholm, Chandrasekhar Natarajan, Roy E. Weber, Jay F. Storz, Angela Fago
Journal: Journal of Experimental Biology
J Exp Biol (2018) 221 (18): jeb185470.
https://doi.org/10.1242/jeb.185470
Published: 17 September 2018
... allosteric regulation in bar-headed goose, a hypoxia-tolerant species renowned for its high-altitude migratory flights. High-altitude Blood Oxygen transport Allostery Adaptation Hypoxia Using flight paths that crest the Himalayas, bar-headed geese ( Anser indicus ) make a roundtrip annual...
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Includes: Supplementary data
Journal Articles

Intramolecular interactions that control voltage sensitivity in the jShak1 potassium channel from Polyorchis penicillatus

Nazlee Sharmin, Warren J. Gallin
Journal: Journal of Experimental Biology
J Exp Biol (2017) 220 (3): 469–477.
https://doi.org/10.1242/jeb.144089
Published: 1 February 2017
... is responsive to amino acid changes in disparate parts of the protein; changes in these different parts interact in complex ways. Allostery Cnidaria Ion channel Structure–function The voltage-gated potassium ion (Kv) channels are transmembrane protein tetramers, consisting of a pore domain (PD...
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Includes: Supplementary data
Journal Articles

Hemoglobin function and allosteric regulation in semi-fossorial rodents (family Sciuridae) with different altitudinal ranges

Inge G. Revsbech, Danielle M. Tufts, Joana Projecto-Garcia, Hideaki Moriyama, Roy E. Weber, Jay F. Storz, Angela Fago
Journal: Journal of Experimental Biology
J Exp Biol (2013) 216 (22): 4264–4271.
https://doi.org/10.1242/jeb.091397
Published: 15 November 2013
.... * Authors for correspondence ( [email protected] ; [email protected] ) COMPETING INTERESTS No competing interests declared. 21 5 2013 7 8 2013 © 2013. Published by The Company of Biologists Ltd 2013 adaptation allostery globin hibernation hypoxia Fossorial...
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Journal Articles

Water regulates oxygen binding in hagfish ( Myxine glutinosa )hemoglobin

Gabriele Müller, Angela Fago, Roy E. Weber
Journal: Journal of Experimental Biology
J Exp Biol (2003) 206 (8): 1389–1395.
https://doi.org/10.1242/jeb.00278
Published: 15 April 2003
... in blood osmolality. * Author for correspondence (e-mail: [email protected] ) 5 2 2003 © The Company of Biologists Limited 2003 2003 water effect allostery hagfish Myxine glutinosa hemoglobin bicarbonate osmolality oxygen affinity cooperativity linkage plot...
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