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J Exp Biol (2018) 221 (13): jeb163840.
Published: 06 July 2018
... skeletal muscle contraction and relaxation. At a cellular level, the dominant effects of obesity are disrupted calcium signalling and 5′-adenosine monophosphate-activated protein kinase (AMPK) activity. As a result, there is a shift from slow to fast muscle fibre types. Decreased AMPK activity promotes...
Cristina Otero-Rodiño, Cristina Velasco, Rosa Álvarez-Otero, Marcos A. López-Patiño, Jesús M. Míguez, José L. Soengas
J Exp Biol (2017) 220 (23): 4410–4417.
Published: 01 December 2017
... of two proteins possibly involved in the modulation of these transcription factors: Akt and AMPK. Therefore, in pooled preparations of hypothalamus incubated for 3 and 6 h in the presence of 2, 4 or 8 mmol l −1 d -glucose, we evaluated the response of parameters related to glucosensing mechanisms...
Marta Librán-Pérez, Inge Geurden, Karine Dias, Genevieve Corraze, Stephane Panserat, José L. Soengas
J Exp Biol (2015) 218 (16): 2610–2619.
Published: 01 August 2015
... protein kinase (AMPK), and proteins involved in cellular signaling such as protein kinase B (Akt) and target of rapamycin (mTOR) display changes that could be related to fatty acid sensing and the control of food intake. The increased levels of fatty acids in the hypothalamus and liver of rainbow trout...
Includes: Supplementary data
J Exp Biol (2014) 217 (10): 1649–1652.
Published: 15 May 2014
...Leonardo J. Magnoni; Arjan P. Palstra; Josep V. Planas AMP-activated protein kinase (AMPK) is well known to be induced by exercise and to mediate important metabolic changes in the skeletal muscle of mammals. Despite the physiological importance of exercise as a modulator of energy use...
Includes: Supplementary data
J Exp Biol (2012) 215 (8): 1373–1383.
Published: 15 April 2012
... receptor 1 adipoR2 adiponectin receptor 2 AMPK AMP-activated protein kinase ASP acid-soluble products FA fatty acid GH growth hormone HSL hormone-sensitive lipase IGF insulin-like growth factor LPL lipoprotein lipase LPS lipopolysaccharide PI3K...
J Exp Biol (2010) 213 (12): 2031–2037.
Published: 15 June 2010
... torpor bouts, dropping their body temperature to near ambient, and cease to feed even if food is present in their cage. The mechanism(s) that regulates food intake in hibernators is unclear. Recently, AMP-activated protein kinase (AMPK) has been shown to play a key role in the central regulation of food...
J Exp Biol (2009) 212 (5): 722–730.
Published: 01 March 2009
... kinase (AMPK)is a major regulator of cellular [ATP] and activates ATP-producing pathways,while inhibiting ATP-consuming pathways. We hypothesized that temperature stress in marine invertebrates activates AMPK to provide adequate concentrations of ATP at increased but sublethal temperatures and that AMPK...