...Travis J. Fleming; Catherine S. Schrankel; Himanshu Vyas; Hannah D. Rosenblatt; Amro Hamdoun ABSTRACT The ABC transporter ABCB1 plays an important role in the disposition of xenobiotics. Embryos of most species express high levels of this transporter in early development as a protective mechanism...

... and xenobiotic compounds. Whether the branchial exchange of organic molecules involves active transporters is currently not known. Here, we investigated the presence, diversity and functional activity of ATP-binding cassette (ABC) transporters in gills of juvenile rainbow trout. By means of RT-qPCR, gene...

... for the existence of ABCC-like efflux transporters in (gastropod) neurons and reports age-associated decline in the extrusion capacity of these transporters. ABC transporter Lymnaea stagnalis Ageing Lipid peroxidation Probenecid MK-571 Cellular homeostasis, the maintenance of a balanced...

.... In mammals, recent evidence suggests that several ABC transporters play important roles in development and organogenesis. Their expression is often enriched in pluripotent stem cells and metastatic or drug resistant tumors, where they can serve as markers in detecting resistance or pluripotency ( Lin et al...

... by using the proton-motive force and (2) ABC transporters ( Fig. 1A , right). Efflux transporters are located in the cytoplasmic membrane. An important efflux system of Gram-negative bacteria is the TetA H + /tetracycline antiporter ( Hinrichs et al . 1994 ). Binding of tetracycline to the TetR...