...Travis J. Fleming; Catherine S. Schrankel; Himanshu Vyas; Hannah D. Rosenblatt; Amro Hamdoun ABSTRACT The ABC transporter ABCB1 plays an important role in the disposition of xenobiotics. Embryos of most species express high levels of this transporter in early development as a protective mechanism...

... and xenobiotic compounds. Whether the branchial exchange of organic molecules involves active transporters is currently not known. Here, we investigated the presence, diversity and functional activity of ATP-binding cassette (ABC) transporters in gills of juvenile rainbow trout. By means of RT-qPCR, gene...

... transporter capacity of L. stagnalis neurons declines with age. We can as yet not answer this question with certainty. However, several studies have shown an age-related attenuation of expression levels of efflux transporters (including ABC transporters) located at the blood–brain barrier ( Erdő and Krajcsi...

... in larval ganglia, with the exception of single cells in the central connective. We discuss the potential implications of this TrnMRP activity on insect development and metabolic resistance. * Author for correspondence ( [email protected] ) 29 11 2010 © 2011. 2011 ABC transporter...

... nucleotide binding fold. As indicated above, this fold is homologous to the hydrophilic ATPase component of bacterial peroplasmic permease. Certain ABC transporters, such as TAP1 and TAP2, are half-molecules with only a single set of membrane-spanning regions and an ATP binding fold. A unique characteristic...