... with the other three authors. COMPETING INTERESTS No competing interests declared. 20 1 2013 12 5 2013 © 2013. Published by The Company of Biologists Ltd 2013 rainbow trout heart glucose 2-deoxyglucose contractility hypoxia reoxygenation adrenaline lactate...

... caused hypoxic hearts to fail early, and hearts perfused with a glucose analogue, 2-deoxyglucose (2-DG), increased glucose uptake 3-fold under hypoxia. The uptake of 2-DG was only partially inhibited when cytochalasin B was added to the medium. Isolated ventricle strips were also incubated...

... glucose uptake cardiac muscle 2-deoxyglucose anoxia contractile activity cytochalasin B hexokinase The heart of fishes, like all vertebrate hearts, has a continuous requirement for energy substrates for the production of ATP and the maintenance of contractile function. Under aerobic...

...Timothy G. West; Peter G. Arthur; Raul K. Suarez; Christopher J. Doll; Peter W. Hochachka ABSTRACT In vivo rates of glucose utilization were estimated in red muscle and heart of rainbow trout using the radiolabeled glucose analogue, [ 14 C]-2-deoxyglucose ([ 14 C]-2-DG). The 2-DG ‘lumped constant...